Institute of Medical Microbiology, Virology and Hygiene, University Medicine Rostock, Rostock, Germany.
Institute of Medical Microbiology, Virology and Hygiene, University Medicine Rostock, Rostock, Germany.
Diagn Microbiol Infect Dis. 2023 Dec;107(4):116054. doi: 10.1016/j.diagmicrobio.2023.116054. Epub 2023 Sep 3.
Phage therapy, particularly for infections due to multi-drug-resistant bacteria, is increasingly gaining in importance. Consecutively, there is a rising need for phage testing in routine diagnostic laboratories. The incubation time of phage susceptibility testing for detecting lytic phage activity on phage/host strain combinations was evaluated. A standardized approach for routine diagnostic laboratories provided reliably detectable lysis zones within 8 hours.
噬菌体治疗,特别是针对多重耐药菌引起的感染,正变得越来越重要。因此,常规诊断实验室对噬菌体检测的需求也在不断增加。本研究评估了噬菌体敏感性检测的孵育时间,以检测噬菌体/宿主菌株组合上的裂解噬菌体活性。为常规诊断实验室提供的标准化方法可在 8 小时内可靠地检测到裂解区。