Reagena Oy, Toivala, Finland.
Medical Center Johanneksen Klinikka, Tampere, Finland.
Clin Physiol Funct Imaging. 2024 Jan;44(1):100-111. doi: 10.1111/cpf.12856. Epub 2023 Oct 2.
To investigate effects of low workload respiratory muscle training (RMT) on respiratory muscle power and lung function in asthmatics, we recruited asthmatic persons who performed a 4-week training programme. The training included 20 daily ex- and inhalations with counter pressure 30% from the individual maximal expiratory pressure (MEP). Lung function was measured before and after the training programme and a follow-up period. The study also included several subjective endpoints for respiratory symptoms. A significant increase in a training group (n = 27) compared with a control group (n = 20) was seen in MEP (+12.4%, vs. +3.5%, p = 0.086), maximal inspiratory pressure (MIP) (+21.1% vs. +0.82%, p = 0.023), slow vital capacity (VC) (+3.7% vs. +1.5%, p = 0.023) and in forced expiratory time (FET, +15.5%, vs. -5.0%, p = 0.022). After being a control for group A, also group B performed similar RMT as group A. In the combined group (A and B, n = 47) MEP (11.3%, p = 0.003), MIP (19.73%, p < 0.001), VC (4.1%, p < 0.001) and FET (14.7%, p < 0.001) increased significantly from the baseline. Changes in other lung function variables were not indicative. On a scale of 1-5, the subjects perceived improvement in reduction of mucus secretion in the airways (median 3, p < 0.001), alleviation of coughing (median 3, p < 0.001) and reduction in dyspnoea (median 3, p < 0.001). As a conclusion, low workload respiratory training of 4 weeks improved respiratory muscle power and increased VC in patients with stable asthma.
为了研究低负荷呼吸肌训练(RMT)对哮喘患者呼吸肌力量和肺功能的影响,我们招募了接受为期 4 周训练计划的哮喘患者。训练包括每天进行 20 次呼气和吸气,对抗压力为个体最大呼气压力(MEP)的 30%。在训练计划前后和随访期间测量肺功能。该研究还包括几个用于呼吸症状的主观终点。与对照组(n=20)相比,训练组(n=27)的 MEP(+12.4%,vs.+3.5%,p=0.086)、最大吸气压力(MIP)(+21.1%,vs.+0.82%,p=0.023)、用力肺活量(VC)(+3.7%,vs.+1.5%,p=0.023)和用力呼气时间(FET,+15.5%,vs.-5.0%,p=0.022)均显著增加。在作为 A 组的对照组之后,B 组也进行了与 A 组相似的 RMT。在联合组(A 和 B,n=47)中,MEP(11.3%,p=0.003)、MIP(19.73%,p<0.001)、VC(4.1%,p<0.001)和 FET(14.7%,p<0.001)从基线显著增加。其他肺功能变量的变化没有指示性。在 1-5 的量表上,受试者感知到气道黏液分泌减少(中位数 3,p<0.001)、咳嗽缓解(中位数 3,p<0.001)和呼吸困难减轻(中位数 3,p<0.001)。总之,4 周的低负荷呼吸训练改善了稳定哮喘患者的呼吸肌力量,并增加了 VC。