El Hussein Mohamed Toufic, Dhaliwal Simreen
Nurse Pract. 2023 Oct 1;48(10):25-32. doi: 10.1097/01.NPR.0000000000000099.
The incidence of human papillomavirus (HPV)-associated head and neck cancer (HNC) has been rapidly increasing in developed countries, with HPV-associated HNC now accounting for 70% of all HNC cases. An increased incidence has been noted particularly among males. The disparities in HPV vaccine uptake rates and the increasing number of individuals with HPV-associated HNC suggest a lack of public awareness of both HPV sequelae and prevention options. This review highlights the importance of prophylactic HPV vaccination for preventing HPV-associated HNC, particularly in males. Current evidence substantiates the need for gender-neutral HPV vaccination programs and reinforces the recommendations made by the CDC. This article raises awareness of the association between HPV and HNC as well as the effectiveness of HPV vaccination in HNC prevention.
在发达国家，人乳头瘤病毒（HPV）相关的头颈癌（HNC）发病率一直在迅速上升，目前HPV相关的HNC占所有HNC病例的70%。发病率上升尤其在男性中较为明显。HPV疫苗接种率的差异以及HPV相关HNC患者数量的增加表明，公众对HPV后遗症和预防措施缺乏认识。本综述强调了预防性HPV疫苗接种对预防HPV相关HNC的重要性，尤其是在男性中。现有证据证实了实施性别中立的HPV疫苗接种计划的必要性，并强化了美国疾病控制与预防中心（CDC）的建议。本文提高了人们对HPV与HNC之间关联以及HPV疫苗接种在预防HNC方面有效性的认识。
