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体外循环对心脏手术后血小板计数的影响：基于病历的回顾性研究。

Effects of extracorporeal circulation with different time on platelet count after cardiac surgery: a retrospective study based on medical records.

机构信息

Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.

出版信息

Sci Rep. 2023 Sep 26;13(1):16071. doi: 10.1038/s41598-023-43334-0.

DOI:10.1038/s41598-023-43334-0
PMID:37752247
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10522614/
Abstract

Our objective was to observe the effects of extracorporeal circulation (ECC) with different time on platelet count in patients undergoing cardiac surgery. A total of 427 patients who underwent elective cardiac surgery under ECC in affiliated hospital of north Sichuan medical college from January 1, 2018 to July 31, 2021 were divided into three groups according to ECC time. We concluded that thrombocytopenia was common after ECC, maximum drop of the platelet counts after ECC was usually seen on the second day after ECC, and platelet counts started to recover on the fifth day after ECC. With the extension of ECC time, the drop in platelet counts is more pronounced, the volume of perioperative blood loss and blood products transfusion are more, and the recovery level and speed of platelet counts is lower.

摘要

我们的目的是观察体外循环（ECC）不同时间对心脏手术患者血小板计数的影响。2018 年 1 月 1 日至 2021 年 7 月 31 日，我院共收治 427 例在 ECC 下行择期心脏手术的患者，根据 ECC 时间分为三组。我们得出结论，ECC 后血小板减少症很常见，ECC 后血小板计数的最大下降通常发生在 ECC 后第二天，ECC 后第五天血小板计数开始恢复。随着 ECC 时间的延长，血小板计数下降更为明显，围手术期出血量和血制品输注量增加，血小板计数的恢复水平和速度降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af4/10522614/fea2db6d7923/41598_2023_43334_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af4/10522614/08a5b716a16e/41598_2023_43334_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af4/10522614/fea2db6d7923/41598_2023_43334_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af4/10522614/08a5b716a16e/41598_2023_43334_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af4/10522614/4c2d50cdaf33/41598_2023_43334_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af4/10522614/d5efe5335d06/41598_2023_43334_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af4/10522614/061e3a965158/41598_2023_43334_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af4/10522614/fea2db6d7923/41598_2023_43334_Fig5_HTML.jpg

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Aging (Albany NY). 2019 Dec 18;11(24):11955-11974. doi: 10.18632/aging.102520.
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Thrombocytopenia After Cardiopulmonary Bypass Is Associated With Increased Morbidity and Mortality.
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