Faiella Eliodoro, Santucci Domiziana, Vertulli Daniele, Russo Fabrizio, Vadalà Gianluca, Papalia Rocco, Beomonte Zobel Bruno, Denaro Vincenzo, Grasso Rosario Francesco
Department of Radiology, University of Rome "Campus Bio-Medico", Via Alvaro del Portillo, 21, 00128 Rome, Italy.
Department of Orthopaedics, University of Rome "Campus Bio-Medico", Via Alvaro del Portillo, 21, 00128 Rome, Italy.
Diseases. 2023 Aug 28;11(3):109. doi: 10.3390/diseases11030109.
The aim of this review is to determine the safety and efficacy of pre-operative spinal metastases embolization procedures. Two reviewers independently conducted the literature search (on MEDLINE databases), including in the review of all the studies that used pre-operative TAE to treat spinal metastases. Twelve articles on pre-operative spinal metastases embolization were selected. Most of the studies demonstrated the low complication rate of pre-operative embolization. The most important study strength is that there are very few reviews in the literature with the setting on pre-operative vertebral metastases embolization. A limitation of the review is that the studies included were predominately retrospective case-control studies, increasing the risk of bias in the primary data. Plus, divergent surgical and embolization procedures were performed in the studies, causing a potential risk of bias in the pooled results. We can conclude that preoperative arterial embolization of vertebral metastases is a safe, well-tolerated technique that reduces surgical blood loss and facilitates surgical tumor resection.
本综述的目的是确定术前脊柱转移瘤栓塞术的安全性和有效性。两名 reviewers 独立进行文献检索(在 MEDLINE 数据库上),包括对所有使用术前经动脉栓塞术(TAE)治疗脊柱转移瘤的研究进行综述。选择了 12 篇关于术前脊柱转移瘤栓塞术的文章。大多数研究表明术前栓塞术的并发症发生率较低。该综述最重要的研究优势在于,文献中很少有关于术前椎体转移瘤栓塞术的综述。该综述的一个局限性是,纳入的研究主要是回顾性病例对照研究,增加了原始数据出现偏差的风险。此外,研究中进行了不同的手术和栓塞程序,导致汇总结果存在潜在的偏差风险。我们可以得出结论,术前椎体转移瘤动脉栓塞术是一种安全、耐受性良好的技术,可减少手术失血并便于手术切除肿瘤。