Khan Rabia S, Aslam Mohsin, Ucer Cemal, Wright Simon
Department of Material Science and Engineering, Faculty of Science of Technology, University of Lancaster, Lancaster LA1 4YR, UK.
ICE Postgraduate Dental Institute and Hospital, University of Salford, 24 Furness Quay, Salford M50 3XZ, UK.
Dent J (Basel). 2023 Sep 13;11(9):215. doi: 10.3390/dj11090215.
Different xenograft approaches in alveolar ridge preservation (ARP) are essential to understand relative to their histomorphometric outcomes. Therefore, the aim of this study involved studying biomaterials of a xenograft nature that are used in ARP procedures, to compare the different approaches and evaluate their efficacy in relation to histomorphometric data. An electronic search was completed using the databases: Ovid (Medline), Google Scholar and Wiley Online Library, including a hand search for relevant articles and grey literature. Only randomised controlled trials, using xenograft biomaterials for alveolar ridge preservation procedures involving human studies, dated from 2010-2022 were included in the review. An initial search yielded 4918 articles, after application of the eligibility criteria, 18 studies were deemed eligible for inclusion in the systematic review. The two main xenograft groups found were of bovine origin and of porcine origin. The main histomorphometric outcomes evaluated included new bone percentage (N.B%) and residual graft percentage (R.G%). The mean N.B% for the bovine and porcine groups were 33.46% and 39.63% respectively and the mean R.G% for the bovine and porcine groups were 19.40% and 18.63% respectively. The current evidence suggests that the two main xenograft biomaterials used in ARP procedures after tooth extraction, which are of bovine and porcine origin, displayed effectiveness in producing new bone.
了解牙槽嵴保存(ARP)中不同的异种移植方法及其组织形态计量学结果至关重要。因此,本研究的目的是研究用于ARP手术的具有异种移植性质的生物材料,比较不同方法,并根据组织形态计量学数据评估其疗效。使用以下数据库完成了电子检索:Ovid(Medline)、谷歌学术和Wiley在线图书馆,包括手工检索相关文章和灰色文献。纳入综述的仅为2010年至2022年期间使用异种移植生物材料进行涉及人体研究的牙槽嵴保存手术的随机对照试验。初步检索得到4918篇文章,应用纳入标准后,18项研究被认为符合纳入系统评价的条件。发现的两个主要异种移植组分别是牛源和猪源。评估的主要组织形态计量学结果包括新骨百分比(N.B%)和剩余移植材料百分比(R.G%)。牛组和猪组的平均N.B%分别为33.46%和39.63%,牛组和猪组的平均R.G%分别为19.40%和18.63%。目前的证据表明,拔牙后ARP手术中使用的两种主要异种移植生物材料,即牛源和猪源材料,在产生新骨方面显示出有效性。