Hamasaki Hidetaka
Hamasaki Clinic, 2-21-4 Nishida, Kagoshima 890-0046, Japan.
Medicines (Basel). 2023 Sep 7;10(9):53. doi: 10.3390/medicines10090053.
Previous research has demonstrated the effectiveness of mindfulness interventions in improving glycemic control. By enhancing attention control, emotion regulation, and self-awareness, mindfulness shows promise in managing the lifestyle factors associated with cardiovascular disease risk. However, the impact of mindfulness on glycemic control in people with diabetes remains unclear. This overview aims to summarize the current evidence of the impact of mindfulness interventions on glycemic control in people with diabetes and propose suggestions for future research. The author searched electronic databases (PubMed/MEDLINE, Embase, and Cochrane Library) to identify relevant systematic reviews and meta-analyses. The current evidence regarding the effects of mindfulness on glycemic control in people with diabetes was summarized. This review evaluated a total of five systematic reviews and meta-analyses of randomized controlled trials (RCTs). Mindfulness interventions show potential for improving glycemic control as measured by hemoglobin A1c (HbA1c) levels, as well as reducing stress, depression, and anxiety in people with diabetes. Four out of five systematic reviews and meta-analyses reported a significant reduction in HbA1c levels by approximately 0.3%. However, the available studies lacked adequate description of key characteristics of study subjects, such as body mass index, medication, and disease conditions, which are essential for assessing the impact of mindfulness on glycemic control. Moreover, there was significant heterogeneity in the intervention methods employed across the included RCTs. Mindfulness interventions are effective in improving glycemic control in people with type 2 diabetes. However, the overall quality of the reviewed studies raises uncertainty regarding the effectiveness of mindfulness as a treatment for people with diabetes. Further research is necessary to elucidate the biological effects of mindfulness on physiological, neurological, and endocrinological functions in humans.
先前的研究已证明正念干预在改善血糖控制方面的有效性。通过增强注意力控制、情绪调节和自我意识,正念在管理与心血管疾病风险相关的生活方式因素方面显示出前景。然而,正念对糖尿病患者血糖控制的影响仍不明确。本综述旨在总结当前关于正念干预对糖尿病患者血糖控制影响的证据,并为未来研究提出建议。作者检索了电子数据库(PubMed/MEDLINE、Embase和Cochrane图书馆)以识别相关的系统评价和荟萃分析。总结了当前关于正念对糖尿病患者血糖控制影响的证据。本综述共评估了五项关于随机对照试验(RCT)的系统评价和荟萃分析。正念干预显示出有潜力改善糖化血红蛋白(HbA1c)水平所衡量的血糖控制,以及减轻糖尿病患者的压力、抑郁和焦虑。五项系统评价和荟萃分析中有四项报告HbA1c水平显著降低约0.3%。然而,现有研究对研究对象的关键特征,如体重指数、用药情况和疾病状况,缺乏充分描述,而这些对于评估正念对血糖控制的影响至关重要。此外,纳入的RCT所采用的干预方法存在显著异质性。正念干预对改善2型糖尿病患者的血糖控制有效。然而,所审查研究的整体质量引发了关于正念作为糖尿病患者治疗方法有效性的不确定性。有必要进行进一步研究以阐明正念对人类生理、神经和内分泌功能的生物学影响。