Kahle M, Filler R D
Chirurgische Klinik des Städtischen Krankenhauses Landshut.
Dtsch Med Wochenschr. 1990 May 18;115(20):784-6. doi: 10.1055/s-2008-1065080.
Two years after a bilateral subtotal thyroidectomy because of nodular goitre a 45-year-old woman noticed a firm nodule on the right side of her neck. Because malignant cells were suspected on cytological examination of a fine-needle biopsy, thyroidectomy was performed which revealed an immature malignant teratoma of the thyroid. A 4 cm local recurrence was noted by computed tomography only three weeks later. Despite chemotherapy (four cycles of vinblastine, cisplatin and bleomycin), radiotherapy to the neck (total dose of 60 Gy) and surgical excision of the infiltrated sternocleidomastoid muscle, bone, liver and lung metastases occurred within 10 months. Four weeks later the patient died of global cardiac failure and tumour cachexia.
一名45岁女性因结节性甲状腺肿接受双侧甲状腺次全切除术后两年，发现颈部右侧有一个质地坚硬的结节。细针穿刺活检的细胞学检查怀疑有恶性细胞，遂进行甲状腺切除术，结果显示为甲状腺未成熟恶性畸胎瘤。仅三周后，计算机断层扫描就发现了4厘米的局部复发。尽管进行了化疗（长春花碱、顺铂和博来霉素四个周期）、颈部放疗（总剂量60 Gy）以及手术切除浸润的胸锁乳突肌、骨骼、肝脏和肺部转移灶，但在10个月内仍出现了转移。四周后，患者死于全心衰竭和肿瘤恶病质。
