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脑膜瘤最新进展:临床-影像学和放射病理学相关性。

Update on meningioma: Clinical-radiological and radio-pathological correlation.

机构信息

Servicio de Radiodiagnóstico, Hospital General Universitario de Castellón, Castellón de la Plana, Castellón, Spain.

Servicio de Anatomía Patológica, Hospital General Universitario de Castellón, Castellón de la Plana, Castellón, Spain.

出版信息

Radiologia (Engl Ed). 2023 Sep-Oct;65(5):458-472. doi: 10.1016/j.rxeng.2023.09.002. Epub 2023 Sep 9.

DOI:10.1016/j.rxeng.2023.09.002
PMID:37758336
Abstract

Meningiomas are tumors that originate in the arachnoid villi and are the most common non-glial neoplasm in the central nervous system. The clinical manifestations associated with meningioma depend, fundamentally, on its location. The location in the cerebral convexity is the most frequent, especially in the frontal lobes, manifesting with headache, motor disturbances, seizures and even neurocognitive disorders. There are 15 histologic subtypes of meningioma and three histologic grades. Within these, grades two and three have a worse prognosis and a higher rate of recurrence, as well as a radiological behavior that is generally more aggressive. Although there are some imaging features that can suggest a specific subtype, the definitive diagnosis will always require histological/molecular confirmation.

摘要

脑膜瘤起源于蛛网膜绒毛,是中枢神经系统最常见的非神经胶质肿瘤。脑膜瘤相关的临床表现主要取决于其位置。大脑凸面是最常见的位置,特别是在额叶,表现为头痛、运动障碍、癫痫发作,甚至神经认知障碍。脑膜瘤有 15 种组织学亚型和 3 种组织学分级。在这些分级中,2 级和 3 级的预后较差,复发率较高,且影像学表现通常更具侵袭性。尽管有一些影像学特征可以提示特定的亚型,但明确的诊断始终需要组织学/分子学的确认。

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