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内吞作用的化学抑制剂：从机制到潜在的临床应用。

The Chemical Inhibitors of Endocytosis: From Mechanisms to Potential Clinical Applications.

机构信息

Department of Synthesis and Technology of Drugs, Medical University of Bialystok, Kilinskiego 1, 15-089 Bialystok, Poland.

Department of Biotechnology, Medical University of Bialystok, Kilinskiego 1, 15-089 Bialystok, Poland.

出版信息

Cells. 2023 Sep 19;12(18):2312. doi: 10.3390/cells12182312.

DOI:10.3390/cells12182312
PMID:37759535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10527932/
Abstract

Endocytosis is one of the major ways cells communicate with their environment. This process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic transformation. Here, we review the approaches to inhibit endocytosis, discuss chemical inhibitors of this process, and discuss potential clinical applications of the endocytosis inhibitors.

摘要

内吞作用是细胞与环境进行交流的主要方式之一。这个过程经常被病原体劫持。内吞作用也参与致癌转化。在这里，我们回顾了抑制内吞作用的方法，讨论了该过程的化学抑制剂，并讨论了内吞作用抑制剂的潜在临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d8b/10527932/6e99394ef313/cells-12-02312-g012.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d8b/10527932/88dd3bb15a75/cells-12-02312-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d8b/10527932/fcba3f84de1e/cells-12-02312-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d8b/10527932/47fac73e6f90/cells-12-02312-g010.jpg
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