Ćirović Milica, Jeličić Ljiljana, Maksimović Slavica, Fatić Saška, Marisavljević Maša, Bošković Matić Tatjana, Subotić Miško
Cognitive Neuroscience Department, Research and Development Institute "Life Activities Advancement Institute", 11000 Belgrade, Serbia.
Department of Speech, Language and Hearing Sciences, Institute for Experimental Phonetics and Speech Pathology, 11000 Belgrade, Serbia.
Diagnostics (Basel). 2023 Sep 8;13(18):2878. doi: 10.3390/diagnostics13182878.
This research aimed to examine the EEG correlates of different stimuli processing instances in a child with ASD and white matter signal abnormalities and to investigate their relationship to the results of behavioral tests. The prospective case study reports two and a half years of follow-up data from a child aged 38 to 66 months. Cognitive, speech-language, sensory, and EEG correlates of auditory-verbal and auditory-visual-verbal information processing were recorded during five test periods, and their mutual interrelation was analyzed. EEG findings revealed no functional theta frequency range redistribution in the frontal regions favoring the left hemisphere during speech processing. The results pointed to a positive linear trend in the relative theta frequency range and a negative linear trend in the relative alpha frequency range when listening to and watching the cartoon. There was a statistically significant correlation between EEG signals and behavioral test results. Based on the obtained results, it may be concluded that EEG signals and their association with the results of behavioral tests should be evaluated with certain restraints considering the characteristics of the stimuli during EEG recording.
本研究旨在检查一名患有自闭症谱系障碍（ASD）且存在白质信号异常的儿童在不同刺激处理情况下的脑电图（EEG）相关性，并研究它们与行为测试结果的关系。这项前瞻性案例研究报告了一名38至66个月大儿童两年半的随访数据。在五个测试阶段记录了听觉-言语和听觉-视觉-言语信息处理的认知、言语-语言、感觉和EEG相关性，并分析了它们之间的相互关系。EEG结果显示，在言语处理过程中，额叶区域没有出现有利于左半球的功能性θ频率范围重新分布。结果表明，在听和看卡通片时，相对θ频率范围呈正线性趋势，相对α频率范围呈负线性趋势。EEG信号与行为测试结果之间存在统计学上的显著相关性。基于所得结果，可以得出结论，考虑到EEG记录期间刺激的特征，应在一定限制条件下评估EEG信号及其与行为测试结果的关联。
