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F-FDG PET/CT与镓标记的成纤维细胞激活蛋白抑制剂（Ga-FAPI）在梭形细胞横纹肌肉瘤中的比较

Comparison of F-FDG PET/CT and Ga-FAPI in Spindle Cell Rhabdomyosarcoma.

作者信息

Shen Zhihui, Wang Ruimin

机构信息

Department of Nuclear Medicine, The First Medical Centre, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing 100853, China.

出版信息

Diagnostics (Basel). 2023 Sep 20;13(18):3006. doi: 10.3390/diagnostics13183006.

DOI:10.3390/diagnostics13183006
PMID:37761371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10530021/
Abstract

We report a rare case of spindle cell rhabdomyosarcoma. Sarcomas generally exhibit an abnormal increased FDG uptake on F-FDG PET/CT imaging, while spindle cell rhabdosarcomas exhibits a significantly increased lesion uptake on Ga FAPI PET/CT imaging compared to F-FDG. This case suggests that Ga-FAPI PET/CT has potential value in evaluating spindle cell rhabdomyosarcoma.

摘要

我们报告了一例罕见的梭形细胞横纹肌肉瘤病例。肉瘤在F-FDG PET/CT成像上通常表现为异常增加的FDG摄取，而与F-FDG相比，梭形细胞横纹肌肉瘤在Ga FAPI PET/CT成像上表现为病变摄取显著增加。该病例表明，Ga-FAPI PET/CT在评估梭形细胞横纹肌肉瘤方面具有潜在价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db7/10530021/19b7167e80c8/diagnostics-13-03006-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db7/10530021/6e448cbd0af6/diagnostics-13-03006-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db7/10530021/48c4180b2265/diagnostics-13-03006-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db7/10530021/19b7167e80c8/diagnostics-13-03006-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db7/10530021/6e448cbd0af6/diagnostics-13-03006-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db7/10530021/48c4180b2265/diagnostics-13-03006-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db7/10530021/19b7167e80c8/diagnostics-13-03006-g003.jpg

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EMBO Mol Med. 2022 Oct 10;14(10):e16001. doi: 10.15252/emmm.202216001. Epub 2022 Aug 2.
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Spindle cell rhabdomyosarcoma in the adult: A rare case report.成人梭形细胞横纹肌肉瘤：一例罕见病例报告。
J Oral Maxillofac Pathol. 2022 Feb;26(Suppl 1):S103-S106. doi: 10.4103/jomfp.jomfp_251_21. Epub 2022 Feb 28.
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Head-to-head evaluation of [F]FDG and [ Ga]Ga-DOTA-FAPI-04 PET/CT in recurrent soft tissue sarcoma.头对头评估 [F]FDG 和 [Ga]Ga-DOTA-FAPI-04 PET/CT 在复发性软组织肉瘤中的应用。
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