Mestermann Stefan, Stonawski Valeska, Böhm Lea, Kratz Oliver, Moll Gunther H, Horndasch Stefanie
Department of Child and Adolescent Mental Health, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Children (Basel). 2023 Sep 5;10(9):1509. doi: 10.3390/children10091509.
Anorexia Nervosa (AN) and Attention Deficit Hyperactivity Disorder (ADHD) are frequent mental disorders in child and adolescent psychiatry. Comorbidity of these disorders is, however, rare among minors. Thus, little is known about their mutual impact on illness development as well as diagnostic and therapeutic influencing factors. We report the case of a 10-year old girl with AN and massive underweight. At the age of 5, ADHD had been diagnosed. Application of ADHD-specific medication had been refused by her caregiver. As of 3rd grade, hyperkinetic symptoms were significantly reduced, which was later linked to beginning AN-induced weight loss. At inpatient admission, no clinically relevant ADHD-related symptoms were present. Accompanying weight gain, rather 'sudden' appearance of attention difficulties, motoric hyperactivity and impulsivity were reported, widely impairing our patient's schoolwork and further daily life. Methylphenidate medication showed good clinical response and tolerability. We hypothesize that the former massive underweight had suppressed ADHD-specific behaviour. AN with significant weight loss could possibly mask hyperkinetic symptoms in children. Thus, sufficient clinical diagnostics and intense monitoring during ED treatment are required. Physicians and therapists should be sensitized for interactions in the joint occurrence of these mental disorders among minors.
神经性厌食症(AN)和注意力缺陷多动障碍(ADHD)是儿童和青少年精神病学中常见的精神障碍。然而,这些障碍在未成年人中的共病情况很少见。因此,人们对它们对疾病发展的相互影响以及诊断和治疗影响因素知之甚少。我们报告了一名10岁患有神经性厌食症且体重严重不足的女孩的病例。她在5岁时被诊断出患有注意力缺陷多动障碍。其照顾者拒绝使用治疗注意力缺陷多动障碍的特定药物。从三年级开始,多动症状明显减轻,这后来与神经性厌食症导致的体重减轻开始有关。住院时,没有出现临床上相关的与注意力缺陷多动障碍相关的症状。随着体重增加,据报告出现了相当“突然”的注意力困难、运动多动和冲动,这严重影响了我们患者的学业和日常生活。哌甲酯药物显示出良好的临床反应和耐受性。我们推测,之前的严重体重不足抑制了与注意力缺陷多动障碍相关的行为。伴有显著体重减轻的神经性厌食症可能会掩盖儿童的多动症状。因此,在急诊治疗期间需要进行充分的临床诊断和密切监测。医生和治疗师应该对这些精神障碍在未成年人中共同出现时的相互作用保持敏感。