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肺切除术后支气管扩张症患者的健康相关生活质量和应激相关障碍

Health-Related Quality of Life and Stress-Related Disorders in Patients with Bronchiectasis after Pulmonary Resection.

作者信息

Nicola Alin, Oancea Cristian, Barata Paula Irina, Adelina Mavrea, Mateescu Tudor, Manolescu Diana, Bratosin Felix, Fericean Roxana Manuela, Pingilati Raja Akshay, Paleru Cristian

机构信息

Department of Thoracic Surgery, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, Romania.

Doctoral School, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.

出版信息

J Pers Med. 2023 Aug 26;13(9):1310. doi: 10.3390/jpm13091310.

Abstract

This multicenter, cross-sectional study investigates the potential correlation between the development of bronchiectasis after lung resection surgery and the health-related quality of life (HRQoL) of the patients. The study aims to provide new insights into the long-term outcomes of patients post-lung resection surgery. The study includes adult patients who underwent lung resection surgery for suspicious lung nodules and developed bronchiectasis within a follow-up period of six months. Bronchiectasis was confirmed by high-resolution computed tomography scans. The patient's health-related quality of life (HRQoL), anxiety, depression, and stress-related disorders were assessed using WHOQOL-BREF, SF-36, HADS, and PSS-10 questionnaires. Out of the 135 patients included in the study, 44 developed bronchiectasis after lung resection surgery. No statistically significant differences were observed between the groups in terms of demographics and medical history. Patients with bronchiectasis demonstrated a lower overall health status, increased deterioration of respiratory symptoms, lower physical activity levels, lower quality of life scores, and experienced more severe anxiety symptoms. Additionally, patients in this group also perceived higher levels of stress; although, the correlation with physical functioning was contradictory. The development of bronchiectasis post-lung resection surgery was associated with poorer quality of life, increased respiratory symptoms, higher anxiety levels, and increased perception of stress. While the correlation between bronchiectasis and HRQoL was statistically significant, the contradictory correlations with stress and physical functioning call for further research. This study underscores the importance of ongoing patient monitoring and the detailed evaluation of respiratory function following lung resection surgery for lung nodules, especially among those who develop bronchiectasis.

摘要

这项多中心横断面研究调查了肺切除手术后支气管扩张的发展与患者健康相关生活质量(HRQoL)之间的潜在相关性。该研究旨在为肺切除手术后患者的长期预后提供新的见解。该研究纳入了因可疑肺结节接受肺切除手术且在六个月随访期内出现支气管扩张的成年患者。支气管扩张通过高分辨率计算机断层扫描得以确诊。使用世界卫生组织生活质量简表(WHOQOL-BREF)、健康调查简表(SF-36)、医院焦虑抑郁量表(HADS)和压力感知量表(PSS-10)问卷对患者的健康相关生活质量、焦虑、抑郁和压力相关障碍进行评估。在该研究纳入的135例患者中,44例在肺切除手术后出现了支气管扩张。两组在人口统计学和病史方面未观察到统计学上的显著差异。患有支气管扩张的患者总体健康状况较低,呼吸道症状恶化加剧,身体活动水平较低,生活质量得分较低,且焦虑症状更严重。此外,该组患者还感觉到更高水平的压力;尽管与身体功能的相关性存在矛盾。肺切除手术后支气管扩张的发生与较差的生活质量、呼吸道症状增加、焦虑水平升高以及压力感知增加有关。虽然支气管扩张与健康相关生活质量之间的相关性具有统计学意义,但与压力和身体功能的矛盾相关性需要进一步研究。这项研究强调了对患者进行持续监测以及对肺结节肺切除手术后呼吸功能进行详细评估的重要性,尤其是在那些发生支气管扩张的患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0271/10532533/2922a146f9e1/jpm-13-01310-g001.jpg

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