Giulini Mario, Brinks Ralph, Vordenbäumen Stefan, Acar Hasan, Richter Jutta G, Baraliakos Xenofon, Ostendorf Benedikt, Schneider Matthias, Sander Oliver, Sewerin Philipp
Department and Hiller-Research-Unit for Rheumatology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Claudiusstrasse 45, 44649 Herne, Germany.
J Pers Med. 2023 Aug 30;13(9):1343. doi: 10.3390/jpm13091343.
Hand Osteoarthritis (HOA) is a frequently occurring musculoskeletal disease that impacts health. Diagnostic criteria often incorporate osteophytes documented through imaging procedures. Radiographic imaging is considered the gold standard; however, more sensitive and safer methods like ultrasound imaging are becoming increasingly important. We conducted a population-based cross-sectional study to examine the prevalence, grade, and pattern of osteophytes using high-resolution ultrasound investigation. Factory workers were recruited on-site for the study. Each participant had 26 finger joints examined using ultrasonography to grade the occurrence of osteophytes on a semi-quantitative scale ranging from 0-3, where higher scores indicate larger osteophytes. A total of 427 participants (mean age 53.5 years, range 20-79 years) were included, resulting in 11,000 joints scored. At least one osteophyte was found in 4546 out of 11,000 (41.3%) joints or in 426 out of 427 (99.8%) participants, but only 5.0% (553) of the joints showed grade 2 or 3 osteophytes. The total osteophyte sum score increased by 0.18 per year as age increased ( < 0.001). The distal interphalangeal joints were the most commonly affected, with 61%, followed by the proximal interphalangeal joints with 48%, carpometacarpal joint 1 with 39%, and metacarpophalangeal joints with 16%. There was no observed impact of gender or workload. In conclusion, ultrasound imaging proves to be a practical screening tool for osteophytes and HOA. Grade 1 osteophytes are often detected in the working population through ultrasound assessments and their incidence increases with age. The occurrence of grade 2 or 3 osteophytes is less frequent and indicates the clinical presence of HOA. Subsequent evaluations are imperative to ascertain the predictive significance of early osteophytes.
手部骨关节炎(HOA)是一种常见的影响健康的肌肉骨骼疾病。诊断标准通常包括通过影像学检查记录的骨赘。放射影像学被认为是金标准;然而,像超声成像这样更敏感、更安全的方法正变得越来越重要。我们进行了一项基于人群的横断面研究,使用高分辨率超声检查来检查骨赘的患病率、分级和模式。在工厂现场招募工人参与研究。每位参与者的26个手指关节接受超声检查,以0至3的半定量量表对骨赘的发生情况进行分级,分数越高表明骨赘越大。总共纳入了427名参与者(平均年龄53.5岁,范围20至79岁),共对11,000个关节进行了评分。在11,000个关节中的4546个(41.3%)或427名参与者中的426名(99.8%)中发现了至少一个骨赘,但只有5.0%(553个)的关节显示为2级或3级骨赘。随着年龄增长,骨赘总分每年增加0.18(<0.001)。远端指间关节受影响最为常见,为61%,其次是近端指间关节,为48%,第一腕掌关节为39%,掌指关节为16%。未观察到性别或工作量的影响。总之,超声成像被证明是一种用于骨赘和手部骨关节炎实用的筛查工具。通过超声评估,在工作人群中经常检测到1级骨赘,其发生率随年龄增加。2级或3级骨赘的发生频率较低,并表明手部骨关节炎的临床存在。后续评估对于确定早期骨赘的预测意义至关重要。