Shamantseva Natalia, Timofeeva Olga, Gvozdeva Alisa, Andreeva Irina, Moshonkina Tatiana
Pavlov Institute of Physiology, Russian Academy of Sciences, 199034 St. Petersburg, Russia.
Life (Basel). 2023 Sep 14;13(9):1909. doi: 10.3390/life13091909.
Transcutaneous electrical stimulation of the spinal cord is used to restore locomotion and body weight support in patients with severe motor disorders. We studied the effects of this non-invasive stimulation on postural control in healthy subjects. Stimulation at the L1-L2 vertebrae was performed to activate the extensor muscles of the lower limbs. Because postural regulation depends on the cognitive style, the effects of the stimulation were analyzed separately in field-dependent (FD) and field-independent (FI) participants. During the study, FD and FI participants ( = 16, 25 ± 5 years, all right dominant leg) stood on a force platform in a soundproof chamber with their eyes closed. Stimulation was applied in the midline between the L1 and L2 vertebrae or over the left or right dorsal roots of the spinal cord; under the control condition, there was no stimulation. Stimulation destabilized posture in healthy subjects, whereas patients with movement disorders usually showed an improvement in postural control. In the FD participants, left dorsal root and midline stimulation increased several postural parameters by up to 30%. Dorsal root stimulation on the side of the supporting leg reduced postural control, while stimulation on the side of the dominant leg did not. No significant changes were observed in the FI participants.
脊髓经皮电刺激用于恢复严重运动障碍患者的运动能力和体重支撑。我们研究了这种非侵入性刺激对健康受试者姿势控制的影响。在L1-L2椎骨处进行刺激以激活下肢的伸肌。由于姿势调节取决于认知方式，因此分别在场依存型（FD）和场独立型（FI）参与者中分析了刺激的效果。在研究过程中，FD和FI参与者（n = 16，25±5岁，均为右利腿）闭着眼睛站在隔音室内的测力平台上。在L1和L2椎骨之间的中线或脊髓的左或右背根上施加刺激；在对照条件下，不进行刺激。刺激使健康受试者的姿势不稳定，而运动障碍患者通常表现出姿势控制的改善。在FD参与者中，左背根和中线刺激使几个姿势参数增加了30%。支撑腿一侧的背根刺激会降低姿势控制，而优势腿一侧的刺激则不会。在FI参与者中未观察到显著变化。
