Shamantseva Natalia, Semenova Varvara, Timofeeva Olga, Andreeva Irina, Moshonkina Tatiana
Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarova Enb., 199034 St. Petersburg, Russia.
Life (Basel). 2024 Nov 29;14(12):1569. doi: 10.3390/life14121569.
The combined effects of transcutaneous electrical stimulation (tES) of the spinal cord and affective sound stimulation on postural control were investigated to elucidate the involvement of spinal networks in the maintenance of vertical stability. Healthy volunteers (n = 27) underwent tES and sound stimulation separately and combined quasi-randomly. All participants were field-dependent; i.e., participants used the exteroceptive afferent stream for spatial orientation. Centre-of-pressure parameters were analysed to assess postural stability. Results showed that tES at the T11-T12 vertebrae stabilised posture, tES at the L1-L2 vertebrae had no postural effect, and sound stimulation from the left destabilised posture. To assess the role of spinal regulation of postural disturbances, we compared the effects of combined tES with sound stimulation to those of sound stimulation alone. Stimulation at the T11-T12 level reduced the lateral sway induced by affective sounds, whereas L1-L2 tES did not. These results suggest that, in healthy individuals, spinal networks located at the T11-T12 and L1-L2 vertebral levels have distinct roles in maintaining upright posture, both when a person is standing still and when they are actively stabilising their posture during destabilising perturbations. T11-T12 spinal networks stabilise upright posture when destabilising information is solely transmitted from the supraspinal level.
研究了脊髓经皮电刺激（tES）和情感声音刺激对姿势控制的联合作用，以阐明脊髓网络在维持垂直稳定性中的作用。健康志愿者（n = 27）分别接受tES和声音刺激，并进行准随机组合。所有参与者均依赖场依存性；即参与者利用外感受传入流进行空间定向。分析压力中心参数以评估姿势稳定性。结果表明，T11 - T12椎骨处的tES可稳定姿势，L1 - L2椎骨处的tES无姿势效应，而来自左侧的声音刺激会破坏姿势稳定性。为评估脊髓对姿势干扰的调节作用，我们比较了tES与声音刺激联合作用与单独声音刺激的效果。T11 - T12水平的刺激减少了情感声音引起的侧向摆动，而L1 - L2 tES则没有。这些结果表明，在健康个体中，位于T11 - T12和L1 - L2椎骨水平的脊髓网络在维持直立姿势方面具有不同作用，无论是在人静止站立时还是在不稳定扰动期间积极稳定姿势时。当不稳定信息仅从脊髓上水平传递时，T11 - T12脊髓网络可稳定直立姿势。
