Department of Human Genetics and Molecular Medicine, Central University of Punjab, Ghudda 151401, India.
Department of Biotechnology, Delhi Technological University, Bawana, Delhi 110042, India.
Medicina (Kaunas). 2023 Aug 31;59(9):1584. doi: 10.3390/medicina59091584.
Autism spectrum disorder (ASD) is a developmental disorder that causes difficulty while socializing and communicating and the performance of stereotyped behavior. ASD is thought to have a variety of causes when accompanied by genetic disorders and environmental variables together, resulting in abnormalities in the brain. A steep rise in ASD has been seen regardless of the numerous behavioral and pharmaceutical therapeutic techniques. Therefore, using complementary and alternative therapies to treat autism could be very significant. Thus, this review is completely focused on non-pharmacological therapeutic interventions which include different diets, supplements, antioxidants, hormones, vitamins and minerals to manage ASD. Additionally, we also focus on complementary and alternative medicine (CAM) therapies, herbal remedies, camel milk and cannabiodiol. Additionally, we concentrate on how palatable phytonutrients provide a fresh glimmer of hope in this situation. Moreover, in addition to phytochemicals/nutraceuticals, it also focuses on various microbiomes, i.e., gut, oral, and vaginal. Therefore, the current comprehensive review opens a new avenue for managing autistic patients through non-pharmacological intervention.
自闭症谱系障碍 (ASD) 是一种发育障碍,导致社交和沟通困难以及刻板行为的表现。当 ASD 伴有遗传障碍和环境变量时,被认为有多种原因,导致大脑异常。无论采用了多少行为和药物治疗技术,自闭症的发病率都在急剧上升。因此,使用补充和替代疗法来治疗自闭症可能非常重要。因此,本综述完全专注于非药物治疗干预措施,包括不同的饮食、补充剂、抗氧化剂、激素、维生素和矿物质来管理 ASD。此外,我们还关注补充和替代医学 (CAM) 疗法、草药、骆驼奶和大麻二醇。此外,我们还专注于美味的植物营养素如何在这种情况下提供新的希望。此外,除了植物化学物质/营养保健品外,它还侧重于各种微生物组,即肠道、口腔和阴道。因此,目前的综合综述为通过非药物干预管理自闭症患者开辟了新途径。