Department of Medicine, University Center UNINOVAFAPI, Teresina 64073-505, Brazil.
Department of Medicine, University Center IDOMED/UniFacid, Teresina 64073-505, Brazil.
Medicina (Kaunas). 2023 Sep 15;59(9):1667. doi: 10.3390/medicina59091667.
: To analyze the influence of parental presence and use of risperidone on social interaction and apathy among patients with Autism Spectrum Disorder (ASD). : Cross-sectional study in a reference center for patients with ASD in a city in northeastern Brazil. The research was carried out using a sociodemographic questionnaire, the Dimensional Apathy Scale, and the Social Communication Questionnaire (SCQ) with the domains of social interaction, language, stereotypy, and communication. The referred questionnaire was answered by the parents or guardians of the children with ASD according to the DSM V criteria. Data were analyzed via independent -test using the SPSS software version 20. : Interviews were conducted with 51 parents/guardians of autistic children with a mean age of 8.8 years (±2.95) and a predominance of males, 34 (66.7%). Of this total, 49 (96.1%) of the children attended school; 40 (78.4%) children were on medication, of which 38 (74.5%) were on risperidone. Those children on risperidone had a higher score on the SCQ scale ( = 0.049) and on the domain of stereotyped behaviors ( = 0.033), which indicated greater impairment. Another statistically relevant variable was the presence of married parents, whereby children who did not have the presence of married parents had a higher average of stereotyped behaviors compared to those who had married parents. : The results showed differences in the means of social interactions for children on risperidone, especially regarding stereotyped behaviors. However, it is not possible to state whether this difference was due to the use of risperidone or whether they used risperidone precisely because of these behaviors. Also important was that children who had the presence of married parents showed fewer stereotyped behaviors. There was no difference in apathetic behavior between children.
: 分析父母在场和使用利培酮对自闭症谱系障碍(ASD)患者社会互动和冷漠的影响。 : 在巴西东北部某城市的 ASD 患者参考中心进行的横断面研究。研究使用了社会人口学问卷、多维冷漠量表和社会交流问卷(SCQ),其中包括社会互动、语言、刻板行为和交流领域。参照问卷由 ASD 儿童的父母或监护人根据 DSM V 标准回答。使用 SPSS 软件版本 20 进行独立检验分析数据。 : 对 51 名自闭症儿童的父母/监护人进行了访谈,他们的平均年龄为 8.8 岁(±2.95),男性居多,占 34 人(66.7%)。在这 51 人中,49 人(96.1%)的孩子上学;40 人(78.4%)的孩子正在服药,其中 38 人(74.5%)服用利培酮。服用利培酮的儿童在 SCQ 量表上的得分更高( = 0.049),在刻板行为领域的得分更高( = 0.033),这表明他们的病情更严重。另一个具有统计学意义的变量是父母是否已婚,没有已婚父母的孩子的刻板行为的平均水平比有已婚父母的孩子更高。 : 结果表明,服用利培酮的儿童在社会互动方面的平均值存在差异,尤其是刻板行为方面。然而,不能确定这种差异是由于使用利培酮引起的,还是因为这些行为而使用了利培酮。同样重要的是,有已婚父母的孩子表现出较少的刻板行为。儿童的冷漠行为没有差异。