在一个大型的、临床转诊的学龄前自闭症谱系障碍（ASD）儿童样本中自闭症症状的性别差异。
Sex-Based Differences in Autism Symptoms in a Large, Clinically-Referred Sample of Preschool-Aged Children with ASD.
作者信息
Stephenson Kevin G, Norris Megan, Butter Eric M
机构信息
Child Development Center, Nationwide Children's Hospital, Columbus, OH, USA.
Departments of Pediatrics and Psychology, The Ohio State University, Columbus, OH, USA.
出版信息
J Autism Dev Disord. 2023 Feb;53(2):624-632. doi: 10.1007/s10803-020-04836-2. Epub 2021 Jan 18.
Previous research has identified possible sex-based differences in restricted and repetitive behaviors in autism spectrum disorder (ASD). However, this finding is mixed, particularly among preschool-aged children. We investigated the presence of sex-based differences in parent-rated ASD symptomatology, using the Autism Spectrum Rating Scale (ASRS). Participants consisted of a large (n = 481,100 female), clinically-referred sample of preschoolers (ages 2-5) diagnosed with ASD (NVIQ: M = 67.11, SD = 21.79). Females had less severe symptoms on the Total, Unusual Behaviors, DSM-5, and Stereotypy scales on the ASRS. The effects were small-to-medium, but statistically significant. There was evidence of differential relationships between nonverbal IQ and ASRS scores among males and females. This study provides additional evidence of sex-based differences in ASD symptoms present from an early age.
先前的研究已经确定了自闭症谱系障碍（ASD）中受限和重复行为可能存在基于性别的差异。然而，这一发现并不一致，尤其是在学龄前儿童中。我们使用自闭症谱系评定量表（ASRS）调查了家长评定的ASD症状学中基于性别的差异。参与者包括一个规模较大（n = 481，100名女性）的临床转诊的学龄前儿童样本（2至5岁），这些儿童被诊断为ASD（非言语智商：M = 67.11，SD = 21.79）。在ASRS的总分、异常行为、DSM-5和刻板行为量表上，女性的症状较轻。这些影响为小到中等程度，但具有统计学意义。有证据表明，男性和女性在非言语智商与ASRS分数之间存在差异关系。这项研究为ASD症状从幼年起就存在基于性别的差异提供了更多证据。
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