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A Review on Treatment-Related Brain Changes in Aphasia.失语症中与治疗相关的脑变化综述。
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J Stroke. 2022 May;24(2):189-206. doi: 10.5853/jos.2022.01102. Epub 2022 May 31.
3
Results of the COMPARE trial of Constraint-induced or Multimodality Aphasia Therapy compared with usual care in chronic post-stroke aphasia.中风后慢性失语症患者的约束诱导或多模式失语症疗法与常规护理对比的COMPARE试验结果。
J Neurol Neurosurg Psychiatry. 2022 Jun;93(6):573-581. doi: 10.1136/jnnp-2021-328422. Epub 2022 Apr 8.
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Better language through chemistry: Augmenting speech-language therapy with pharmacotherapy in the treatment of aphasia.通过化学手段改善语言:在失语症治疗中用药物治疗增强言语语言治疗。
Handb Clin Neurol. 2022;185:261-272. doi: 10.1016/B978-0-12-823384-9.00013-X.
5
The Effectiveness of Transcranial Magnetic Stimulation (TMS) Paradigms as Treatment Options for Recovery of Language Deficits in Chronic Poststroke Aphasia.经颅磁刺激(TMS)范式治疗慢性脑卒中后失语症语言缺陷的疗效。
Behav Neurol. 2022 Jan 11;2022:7274115. doi: 10.1155/2022/7274115. eCollection 2022.
6
Transcranial Magnetic Stimulation and Working Memory Training to Address Language Impairments in Aphasia: A Case Study.经颅磁刺激和工作记忆训练治疗失语症的语言障碍:个案研究。
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卒中后失语症康复领域的治疗方法和挑战:现状与未来展望。

Therapies and Challenges in the Post-Stroke Aphasia Rehabilitation Arena: Current and Future Prospects.

机构信息

The Brain and Neurorehabilitation Lab, Department of Rehabilitation Sciences, Cyprus University of Technology, 3041 Limassol, Cyprus.

出版信息

Medicina (Kaunas). 2023 Sep 17;59(9):1674. doi: 10.3390/medicina59091674.

DOI:10.3390/medicina59091674
PMID:37763793
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10537631/
Abstract

Aphasia is a serious consequence of stroke that results in a breakdown in communication. The course of aphasia recovery differs between afflicted individuals, and responsiveness to treatment cannot be predicted. Aphasiologists continue to investigate numerous behavioral treatment protocols that have shifted their focus to complimentary rehabilitation strategies. The aim of this study is threefold. First, to summarize the different categories of aphasia interventions post-stroke, considering their respective protocols, and present available evidence on the effectiveness of those protocols. Second, to document the challenges regarding the prediction of aphasia treatment response post-stroke in individual patients. Third, to report the challenges faced by researchers in recruiting people with aphasia (PWA) for treatment studies, and provide recommendations on how to increase participant recruitment and retention. This study provides up-to-date information on (i) effective therapies and aphasia recovery processes, and (ii) research recruitment hurdles together with potential strategies for overcoming them.

摘要

失语症是中风的严重后果,导致沟通障碍。失语症的恢复过程因人而异,对治疗的反应无法预测。失语症学家继续研究许多行为治疗方案,这些方案将重点转移到补充康复策略上。本研究有三个目的。首先,总结中风后不同类别的失语症干预措施,考虑其各自的方案,并介绍这些方案有效性的现有证据。其次,记录在个体患者中预测中风后失语症治疗反应的挑战。第三,报告研究人员在招募失语症患者(PWA)进行治疗研究方面面临的挑战,并就如何增加参与者的招募和保留提出建议。本研究提供了关于(i)有效治疗和失语症恢复过程,以及(ii)研究招募障碍及其潜在克服策略的最新信息。