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Revisiting the Intestinal Microbiome and Its Role in Diarrhea and Constipation.

作者信息

Iancu Mihaela Adela, Profir Monica, Roşu Oana Alexandra, Ionescu Ruxandra Florentina, Cretoiu Sanda Maria, Gaspar Bogdan Severus

机构信息

Department of Family Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Department of Oncology, Elias University Emergency Hospital, 011461 Bucharest, Romania.

出版信息

Microorganisms. 2023 Aug 29;11(9):2177. doi: 10.3390/microorganisms11092177.


DOI:10.3390/microorganisms11092177
PMID:37764021
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10538221/
Abstract

The gut microbiota represents a community of microorganisms (bacteria, fungi, archaea, viruses, and protozoa) that colonize the gut and are responsible for gut mucosal structural integrity and immune and metabolic homeostasis. The relationship between the gut microbiome and human health has been intensively researched in the past years. It is now widely recognized that gut microbial composition is highly responsible for the general health of the host. Among the diseases that have been linked to an altered gut microbial population are diarrheal illnesses and functional constipation. The capacity of probiotics to modulate the gut microbiome population, strengthen the intestinal barrier, and modulate the immune system together with their antioxidant properties have encouraged the research of probiotic therapy in many gastrointestinal afflictions. Dietary and lifestyle changes and the use of probiotics seem to play an important role in easing constipation and effectively alleviating diarrhea by suppressing the germs involved. This review aims to describe how probiotic bacteria and the use of specific strains could interfere and bring benefits as an associated treatment for diarrhea and constipation.

摘要

相似文献

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J Fungi (Basel). 2025-4-22

[2]
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[3]
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[4]
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[5]
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[6]
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[7]
Polysaccharides of natural products alleviate antibiotic-associated diarrhea by regulating gut microbiota: a review.

Arch Microbiol. 2024-11-7

[8]
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[9]
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[10]
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本文引用的文献

[1]
Diarrhea accompanies intestinal inflammation and intestinal mucosal microbiota dysbiosis during fatigue combined with a high-fat diet.

BMC Microbiol. 2023-5-25

[2]
American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation.

Gastroenterology. 2023-6

[3]
Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial.

Gut Microbes. 2023

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Nutrients. 2023-3-28

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Ther Adv Infect Dis. 2023-2-24

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Intestinal dysbiosis exacerbates the pathogenesis of psoriasis-like phenotype through changes in fatty acid metabolism.

Signal Transduct Target Ther. 2023-1-30

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J Clin Med. 2022-11-8

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Int J Mol Sci. 2022-10-25

[9]
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Front Microbiol. 2022-10-11

[10]
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Cells. 2022-10-17

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