Hammer C, Krebs G, Chaussy C, Pfeifer K, Schmidt K, Land W, Brendel W
Transplant Proc. 1979 Mar;11(1):31-5.
In HR, primarily humoral immunologic factors trigger a sequence of events that finally destroys the transplanted organ. Unspecific trapping of WBC diminishes the RBF, especially in the first compartment--the cortex. Pretreatment with ALG is able to suppress this cellular participation partially, thus postponing the stop of RBF without preventing the influence of humoral factors on the graft. As shown by pathologic and functional criteria recorded for 8 hr, an exclusive measurement of total RBF does not reflect an inhibition of the course of HR.
在超急性排斥反应中，主要是体液免疫因素引发一系列最终导致移植器官被破坏的事件。白细胞的非特异性截留会减少肾血流量（RBF），尤其是在第一个区域——皮质。用抗淋巴细胞球蛋白（ALG）预处理能够部分抑制这种细胞参与，从而推迟肾血流量的停止，而不会阻止体液因素对移植物的影响。根据记录8小时的病理和功能标准显示，仅测量总肾血流量并不能反映超急性排斥反应进程的抑制情况。
