抗淋巴细胞球蛋白在同种异体肾移植排斥反应中的应用。一项对照研究。
The use of antilymphocyte globulin in renal allograft rejection. A controlled study.
作者信息
Birkeland S A
出版信息
Postgrad Med J. 1976;52(5 Suppl):82-8.
A controlled clinical investigation of the effect of equine anti-human-lymphocyte globulin (ALG) on established rejection after transplantation was carried out. In comparison with a control group, the treated group showed a significantly positive effect of ALG in the form of a faster reversal of rejection episodes (P less than 0-05). Leucocytes, lymphocytes, erythrocytes, thrombocytes and immunoglobulins were unaffected by the treatment, but there were signs of a complement consuming process and an influence on blast transformation tests. No rise in antibody titre against equine globulin was seen.
进行了一项关于马抗人淋巴细胞球蛋白（ALG）对移植后已发生的排斥反应影响的对照临床研究。与对照组相比，治疗组显示出ALG具有显著的积极效果，表现为排斥反应发作逆转更快（P小于0.05）。白细胞、淋巴细胞、红细胞、血小板和免疫球蛋白未受治疗影响，但有补体消耗过程的迹象以及对母细胞转化试验有影响。未观察到针对马球蛋白的抗体滴度升高。
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