Kagizman Salim Cagatay, Hocaoglu Cicek
Hitit University Erol Olcok Training and Research Hospital, Department of Psychiatry, Corum, Turkey.
Recep Tayyip Erdogan University Faculty of Medicine, Department of Psychiatry, Rize, Turkey.
Medeni Med J. 2023 Sep 28;38(3):218-231. doi: 10.4274/MMJ.galenos.2023.13707.
Oxytocin is a peptide hormone that is most known for its role in reproduction. However, many effects other than reproduction have been defined. The lifetime prevalence of mental disorders is approximately 20%, and they have a significant ratio among the diseases that lead to disability. Treatment resistance may cause the mental disorder to become chronic and increase disability. With the examination of the oxytocinergic system, both the elucidation of the etiology of the diseases and their evaluation as a new treatment option have come to the fore. In various studies, it has been desired to create a more effective treatment model by measuring the level of oxytocin in psychiatric disorders, examining its receptor, and applying exogenous oxytocin in the treatment. In this review, an overview of oxytocin's efficacy in treatment is presented by considering the relationship between psychiatric disorders and the oxytocinergic system.
催产素是一种肽类激素，最为人所知的是其在生殖过程中的作用。然而，除生殖作用外，它还有许多其他作用已被明确。精神障碍的终生患病率约为20%，在导致残疾的疾病中占比显著。治疗抵抗可能导致精神障碍转为慢性并增加残疾程度。随着对催产素能系统的研究，疾病病因的阐明以及将其作为一种新的治疗选择进行评估都变得尤为重要。在各种研究中，人们希望通过测量精神疾病中催产素的水平、检查其受体并在治疗中应用外源性催产素，来创建一种更有效的治疗模式。在这篇综述中，通过考虑精神疾病与催产素能系统之间的关系，对催产素在治疗中的疗效进行了概述。
