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48岁男性患者的胃海绵状血管瘤:一例罕见的表现为上消化道出血症状的病例。

Gastric cavernous hemangioma in 48-years male patient: a rare case presenting upper gastrointestinal bleeding manifestations.

作者信息

Sukmagautama Coana, Asaduddin Aiman Hilmi, A'malia Ulya, Putri Desy Puspa

机构信息

Internal Medicine Department, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.

Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.

出版信息

Gastroenterol Hepatol Bed Bench. 2023;16(3):336-340. doi: 10.22037/ghfbb.v16i2.2773.

Abstract

Gastric hemangioma (GH) is a rare benign tumor that may cause to upper gastrointestinal bleeding. Furthermore, this condition could lead life-threatening conditions thus should be recognized sooner to minimize unnecessary invasive surgical intervention, and accident. We reported a 48 years old man which came to emergency room (ER) with the chief complaint of hematemesis and black stool accompanied by abdominal pain, cold sweat, body weakness and enlarger stomach. Physical examination showed slightly icteric eye, and conjunctival pallor. On palpation, the epigastric and right upper quadrant was tender, and occult blood was detected in the excrement. A minor microcytic hypochromic anemia, absolute neutrophilia, hypoalbuminemia, and an increase in urea and creatinine were determined by laboratory tests. Moreover, the esophagogastroduodenoscopy was performed, and showed broad mass with dilated blood vessels. The histopathological examination result showed gastric mass with the histological erythrocyte extravasation. The diagnosis was hematemesis melena owing to cavernous GH with differential diagnosis of hematoma, and other gastric mass, with anemia gravis. For the treatment, patient received fluid resuscitation, omeprazole, tranexamic acid, somatostatin, and antibiotics. He received two kolfs transfusion of packed red cell. Gastric hemangiomas are benign vascular tumors that can lead to severe gastrointestinal bleeding. These benign tumors are lesions that develop as a result of endothelial cell proliferation, and concomitant pericytic hyperplasia, which leads to a collection of dilated vessels. The cavernous subtype of GHs often comprises of bigger blood-filled areas and larger blood vessels. It is more likely for the cavernous GH to rupture, leading to substantial bleeding. Endoscopic assessment is important in the patients with upper GI bleeding, and GH appear as well-circumscribed vascular submucosal mass. Although this disease is benign with a lower recurrence, we suggest for further surgical treatment and the requirement for long-term follow-up to assess the outcome.

摘要

胃血管瘤(GH)是一种罕见的良性肿瘤,可能导致上消化道出血。此外,这种情况可能导致危及生命的状况,因此应尽早识别,以尽量减少不必要的侵入性手术干预和意外情况。我们报告了一名48岁男性,他因呕血、黑便伴腹痛、冷汗、身体虚弱和胃部肿大前来急诊室(ER)。体格检查显示眼睛轻度黄疸,结膜苍白。触诊时,上腹部和右上腹压痛,粪便潜血阳性。实验室检查确定有轻度小细胞低色素性贫血、绝对中性粒细胞增多、低白蛋白血症以及尿素和肌酐升高。此外,进行了食管胃十二指肠镜检查,显示有广泛的肿块和扩张的血管。组织病理学检查结果显示胃肿块有组织学上的红细胞外渗。诊断为由于海绵状GH导致的呕血黑便,鉴别诊断包括血肿和其他胃肿块,伴有严重贫血。治疗方面,患者接受了液体复苏、奥美拉唑、氨甲环酸、生长抑素和抗生素治疗。他接受了两次浓缩红细胞的科耳夫输血。胃血管瘤是良性血管肿瘤,可导致严重的胃肠道出血。这些良性肿瘤是由于内皮细胞增殖以及伴随的周细胞增生而形成的病变,导致扩张血管的聚集。GH的海绵状亚型通常由更大的充血区域和更大的血管组成。海绵状GH更有可能破裂,导致大量出血。内镜评估对上消化道出血患者很重要,GH表现为边界清晰的血管性黏膜下肿块。虽然这种疾病是良性的,复发率较低,但我们建议进一步手术治疗并需要长期随访以评估结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4262/10520390/2e9a70becb8f/GHFBB-16-336-g001.jpg

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