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一名使用普萘洛尔治疗的胃血管瘤新生儿。

A Newborn with Gastric Hemangioma Treated Using Propranolol.

作者信息

Kaya Huseyin, Gokce Ismail Kursad, Gungor Sukru, Turgut Hatice, Ozdemir Ramazan

机构信息

Division of Neonatology, Department of Pediatrics, Turgut Ozal Medical Center, Inonu University School of Medicine, Malatya, Turkey.

Division of Pediatric Gastroenterology, Department of Pediatrics, Turgut Ozal Medical Center, Inonu University School of Medicine, Malatya, Turkey.

出版信息

Pediatr Gastroenterol Hepatol Nutr. 2018 Oct;21(4):341-346. doi: 10.5223/pghn.2018.21.4.341. Epub 2018 Oct 10.

Abstract

Gastric hemangiomas are rare benign vascular tumors that can cause severe gastrointestinal system bleeding. We presented the case of a neonate with fresh bleeding and melena from the orogastric tube and detected gastric hemangioma in esophagogastroduodenoscopic examination. Propranolol is widely used in treatment of cutaneous hemangiomas and non-gastric gastrointestinal system hemangiomas. However, the surgical approach is preferred for treating gastric hemangiomas, and there are few reports of gastric hemangiomas associated with non-surgical treatment. Gastric hemorrhage decreased with antacid and somatostatin treatment. Propranolol treatment was initiated before the surgery decision. After three weeks of treatment, we observed regression in the hemangioma with endoscopic evaluation. During the course of treatment, the patient's gastrointestinal system bleeding did not recur, and there were no side effects associated with propranolol.

摘要

胃血管瘤是罕见的良性血管肿瘤,可导致严重的胃肠道系统出血。我们报告了一例新生儿,经口胃管出现新鲜出血和黑便,在食管胃十二指肠镜检查中发现胃血管瘤。普萘洛尔广泛用于治疗皮肤血管瘤和非胃胃肠道系统血管瘤。然而,手术方法是治疗胃血管瘤的首选,与非手术治疗相关的胃血管瘤报道较少。使用抗酸剂和生长抑素治疗后胃出血减少。在决定手术前开始使用普萘洛尔治疗。治疗三周后,通过内镜评估观察到血管瘤缩小。在治疗过程中,患者的胃肠道系统出血未复发,且未出现与普萘洛尔相关的副作用。

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