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三种多重耐药性尿路致病性细菌的完整封闭基因组序列

Complete closed genome sequences of three multidrug-resistant uropathogenic .

作者信息

Guragain Manita, Kanrar Siddhartha, Bagi Lori, Chen Chin-Yi

机构信息

U.S. Department of Agriculture, Agriculture Research Service, Eastern Regional Research Center, Molecular Characterization of Foodborne Pathogens Research Unit, Wyndmoor, Pennsylvania, USA.

出版信息

Microbiol Resour Announc. 2023 Oct 19;12(10):e0042223. doi: 10.1128/MRA.00422-23. Epub 2023 Sep 28.

DOI:10.1128/MRA.00422-23
PMID:37768048
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10586095/
Abstract

Infection by antibiotic-resistant extraintestinal pathogenic may result in treatment failure and thus pose a serious public health threat. Here we report the complete closed genome sequence of three multidrug-resistant (MDR) human uropathogenic isolates using long-read sequencing technology and assembly.

摘要

耐抗生素的肠道外致病性细菌感染可能导致治疗失败,从而对公共卫生构成严重威胁。在此,我们报告了使用长读测序技术和组装技术对三株多重耐药(MDR)人尿道致病性细菌分离株的完整封闭基因组序列。

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本文引用的文献

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Use of Large-Scale Genomics to Identify the Role of Animals and Foods as Potential Sources of Extraintestinal Pathogenic Escherichia coli That Cause Human Illness.利用大规模基因组学确定动物和食物作为导致人类疾病的肠外致病性大肠杆菌潜在来源的作用。
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Global, regional, and national burden of urinary tract infections from 1990 to 2019: an analysis of the global burden of disease study 2019.全球、区域和国家尿路系统感染负担:2019 年全球疾病负担研究分析。
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Assembly of long, error-prone reads using repeat graphs.使用重复图组装长的、易错的读取。
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PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens.PointFinder:一种基于 WGS 的新型网络工具,用于检测细菌病原体中与染色体点突变相关的抗菌药物耐药性。
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Genome Biol. 2015 Dec 29;16:294. doi: 10.1186/s13059-015-0849-0.
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Urinary tract infections: epidemiology, mechanisms of infection and treatment options.尿路感染:流行病学、感染机制及治疗选择
Nat Rev Microbiol. 2015 May;13(5):269-84. doi: 10.1038/nrmicro3432. Epub 2015 Apr 8.
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Human and avian extraintestinal pathogenic Escherichia coli: infections, zoonotic risks, and antibiotic resistance trends.人源和禽源肠道外致病性大肠杆菌:感染、人畜共患病风险和抗生素耐药趋势。
Foodborne Pathog Dis. 2013 Nov;10(11):916-32. doi: 10.1089/fpd.2013.1533. Epub 2013 Aug 20.
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BLAST+: architecture and applications.BLAST+:体系结构与应用。
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