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噬菌体NTEC3针对多重耐药性尿路致病性和广泛耐药性尿路致病性分离株的全基因组测序及活性数据。

Whole genome sequencing and activity data of phage NTEC3 against multidrug-resistant Uropathogenic and extensively drug-resistant Uropathogenic isolates.

作者信息

Chaudhary Naveen, Singh Dharminder, Maurya Ravi Kumar, Mohan Balvinder, Mavuduru Ravimohan S, Taneja Neelam

机构信息

Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Urology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Data Brief. 2022 Jul 18;43:108479. doi: 10.1016/j.dib.2022.108479. eCollection 2022 Aug.

Abstract

This data article describes the whole-genome sequencing and  activity data of  phage NTEC3 isolated from a community sewage sample in Chandigarh, India. The phage NTEC3 was active against multi-drug-resistant (MDR) and extensively drug-resistant (XDR) biofilm-forming Uropathogenic (UPEC) strains. The genome of this phage was linear, double-stranded, and 44.2 kb long in size. A total of 72 ORFs (open reading frames) were predicted and 30 ORFs were encoded for functional proteins. The phage belonged to the  genus of the  family. Phylogenetic analysis using DNA polymerase was performed to understand the phage evolutionary relationships. Genes encoding for lysogeny, virulence, toxins, antibiotic resistance, and the CRISPR/CRISPR-like system were not found during screening. The annotated genome was deposited in Genbank under the accession number OK539620.

摘要

本文描述了从印度昌迪加尔的一份社区污水样本中分离出的噬菌体NTEC3的全基因组测序和活性数据。噬菌体NTEC3对多重耐药(MDR)和广泛耐药(XDR)的形成生物膜的尿路致病性大肠杆菌(UPEC)菌株具有活性。该噬菌体的基因组是线性双链的,大小为44.2 kb。总共预测了72个开放阅读框(ORF),其中30个ORF编码功能蛋白。该噬菌体属于该科的属。使用DNA聚合酶进行了系统发育分析,以了解噬菌体的进化关系。在筛选过程中未发现编码溶原性、毒力、毒素、抗生素抗性和CRISPR/类CRISPR系统的基因。注释后的基因组已保存在Genbank中,登录号为OK539620。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95af/9340528/84a370c885ba/gr1.jpg

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