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德克萨斯州黑人跨性别 HIV 阴性女性未来 3 个月计划使用 PrEP 的相关因素及其使用 PrEP 的可能性。

Factors Associated with Planned Future Use of PrEP in the Next 3 Months and Likelihood to Use PrEP Among Black Cisgender HIV-negative Women in Texas.

机构信息

Department of Health Promotion and Disease Prevention, Robert Stempel College of Public Health & Social Work, Florida International University, 11200 S.W. 8th Street, AHC5, Miami, FL, 33199, USA.

School of Nursing, Vanderbilt University, Nashville, TN, USA.

出版信息

AIDS Behav. 2024 Jan;28(1):72-92. doi: 10.1007/s10461-023-04188-9. Epub 2023 Sep 28.

Abstract

Identifying and then addressing barriers and leveraging facilitators is important to help increase pre-exposure prophylaxis (PrEP) use among Black women vulnerable to HIV acquisition. The present cross-sectional study examined what factors were associated with future plans to use PrEP, and general likelihood to use it among a convenience sample of 152 adult, Black cisgender women from three metropolitan areas in Texas. The final multivariable logistic regression model revealed that relationship status (aOR = 0.20, 95% CI: 0.05-0.73, p < 0.05), PrEP anticipated stigma (aOR = 0.29, 95% CI: 0.10-0.78, p < 0.05), perceived discrimination (aOR = 0.40, 95% CI: 0.21-0.78, p < 0.01) and interest in learning more about PrEP (aOR = 5.32, 95% CI: 2.60-10.9, p < 0.001) were associated with future plans to use PrEP. The final multivariable linear regression model with maximum likelihood estimation identified that perceived discrimination (β=-0.24, SE: -0.38 - -0.10, p < 0.01), perceived HIV risk (β = 0.33, SE: 0.18-0.49, p < 0.001), willingness to use PrEP with condoms (β = 1.26, SE: 0.94-1.60, p < 0.001), and comfort communicating about PrEP with a provider (β = 0.23, SE: 0.06-0.41, p < 0.01) were associated with general likelihood to use PrEP. Findings reveal key factors that warrant further attention and examination toward improving PrEP use within this population.

摘要

确定并解决障碍,利用促进因素,对于帮助增加面临 HIV 感染风险的黑人女性使用暴露前预防(PrEP)药物至关重要。本横断面研究调查了哪些因素与未来使用 PrEP 的计划以及在德克萨斯州三个大都市区的 152 名成年黑人顺性别女性的便利性样本中使用 PrEP 的总体可能性相关。最终的多变量逻辑回归模型显示,关系状况(OR = 0.20,95%CI:0.05-0.73,p < 0.05)、PrEP 预期耻辱感(OR = 0.29,95%CI:0.10-0.78,p < 0.05)、感知歧视(OR = 0.40,95%CI:0.21-0.78,p < 0.01)和对了解更多 PrEP 的兴趣(OR = 5.32,95%CI:2.60-10.9,p < 0.001)与未来使用 PrEP 的计划相关。采用最大似然估计的最终多变量线性回归模型确定,感知歧视(β=-0.24,SE:-0.38-0.10,p < 0.01)、感知 HIV 风险(β=0.33,SE:0.18-0.49,p < 0.001)、愿意在使用避孕套时使用 PrEP(β=1.26,SE:0.94-1.60,p < 0.001)和与提供者就 PrEP 进行沟通的舒适度(β=0.23,SE:0.06-0.41,p < 0.01)与普遍使用 PrEP 的可能性相关。研究结果揭示了关键因素,值得进一步关注和研究,以提高该人群中 PrEP 的使用率。

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