Clinic for Endocrinology, Nephrology, and Rheumatology, Leipzig University Medical Center, Liebigstrasse 20, 04103, Leipzig, Germany.
Helmholtz Institute for Metabolic, Obesity and Vascular Research, Philipp-Rosenthal-Strasse 27, 04103, Leipzig, Germany.
Sci Rep. 2023 Sep 28;13(1):16297. doi: 10.1038/s41598-023-43509-9.
This study evaluated the impact of obesity on abdominal ultrasound diagnostics and assessed effect of high-performance ultrasound probes increased imaging quality. Lean and obese subjects (n = 40; 58% female) were categorized according to body mass index (BMI, 21 to 48 kg/m). A highly standardized ultrasound examination of the abdomen was performed by trained examiners using three different probes in randomized order (standard probe versus two high-performance probes). Quality of B-mode and duplex ultrasound were assessed using a custom scoring approach for depiction of liver and kidney anatomy and vascularization. Across probes, imaging quality of hepatic and kidney anatomy was inversely related with BMI (P < 0.03, r < - 0.35). Age, sex, and BMI explained 51% of the variance within the ultrasound quality score, with β = - 0.35, P < 0.0001 for BMI. Compared to the standard probe, high-performance probes allowed for a better depiction of kidney and liver anatomy in subjects above BMI 35 kg/m (n = 20, all P < 0.05), resulting in a less pronounced deterioration of imaging quality with increased BMI (all P < 0.05). In conclusion the study shows that obesity impairs ultrasound imaging quality of abdominal anatomy. The application of high-performance probes can increase anatomic depiction in obese patients.Registration number of the German Registry of Clinical Studies: DRKS00023498.
本研究评估了肥胖对腹部超声诊断的影响，并评估了高性能超声探头提高成像质量的效果。根据身体质量指数（BMI，21 至 48kg/m）将瘦和肥胖受试者（n=40；58%为女性）分为两类。由经过培训的检查人员使用三种不同的探头（标准探头与两种高性能探头）以高度标准化的方式对腹部进行超声检查。使用自定义评分方法评估 B 模式和双工超声的图像质量，以评估肝和肾解剖结构和血管化的图像质量。在所有探头中，肝和肾解剖结构的成像质量与 BMI 呈负相关（P<0.03，r <-0.35）。年龄、性别和 BMI 解释了超声质量评分内 51%的方差，β=-0.35，P<0.0001。与标准探头相比，在 BMI 超过 35kg/m 的患者中，高性能探头可以更好地显示肾脏和肝脏解剖结构（n=20，所有 P<0.05），从而降低了 BMI 增加导致的成像质量恶化程度（所有 P<0.05）。总之，本研究表明肥胖会损害腹部解剖结构的超声成像质量。应用高性能探头可以增加肥胖患者的解剖结构描绘能力。德国临床研究注册编号：DRKS00023498。
