Ba-Shammakh Saleh A, Al Jayyousi Obada A, Abu-Hussein Mohammad, Abokhsab Mahmoud M, Al-Thnaibat Mohammad H, Haj-Freej Hasn M, Al-Bourah Abdulrahman M
General Surgery, The Islamic Hospital, Amman, JOR.
Medicine, Jordan University of Science and Technology, Al Ramtha, JOR.
Cureus. 2023 Aug 27;15(8):e44229. doi: 10.7759/cureus.44229. eCollection 2023 Aug.
Oncologic disorders, such as lung adenocarcinoma, can intricately interplay with the coagulation cascade, often leading to thromboembolic events, of which deep vein thrombosis (DVT) stands out prominently. In this report, we present a unique case of a 50-year-old non-smoking Jordanian male who exhibited bilateral DVT as an unexpected preliminary manifestation of an aggressive lung adenocarcinoma. Although the patient did not possess common risk factors for DVT, the bilateral presentation drew attention to the possibility of an underlying malignancy. Subsequent investigations revealed a stage 4 primary lung adenocarcinoma. This case underscores the imperative of maintaining a broad differential in cases of DVT, especially when presenting bilaterally and without evident etiology. Such early detection and intervention, accompanied by collaborative medical strategies and specialized care, can play a pivotal role in enhancing patient prognosis and survival rates. This case exemplifies the potential of DVT, particularly when bilateral, as a harbinger of a more sinister underlying pathology like lung adenocarcinoma.
肿瘤性疾病,如肺腺癌,可与凝血级联发生复杂的相互作用,常常导致血栓栓塞事件,其中深静脉血栓形成(DVT)尤为突出。在本报告中,我们介绍了一例独特的病例,一名50岁不吸烟的约旦男性,其双侧DVT是侵袭性肺腺癌意想不到的首发表现。尽管该患者没有DVT的常见危险因素,但双侧表现引起了对潜在恶性肿瘤可能性的关注。随后的检查发现为4期原发性肺腺癌。该病例强调了在DVT病例中保持广泛鉴别诊断的必要性,特别是当双侧出现且无明显病因时。这种早期检测和干预,辅以协作性医疗策略和专科护理,可在提高患者预后和生存率方面发挥关键作用。该病例例证了DVT,尤其是双侧DVT,作为更隐匿的潜在病理如肺腺癌先兆的可能性。