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缄默症:综述、鉴别诊断及22例报告

Mutism: review, differential diagnosis, and report of 22 cases.

作者信息

Altshuler L L, Cummings J L, Mills M J

出版信息

Am J Psychiatry. 1986 Nov;143(11):1409-14. doi: 10.1176/ajp.143.11.1409.

DOI:10.1176/ajp.143.11.1409
PMID:3777229
Abstract

Mutism is a common manifestation of both psychiatric and neurologic illness. Psychiatric disturbances associated with mutism include schizophrenia, affective disorders, conversion reactions, dissociative states, and dementias. Neurologic disorders producing mutism involve the basal ganglia, frontal lobes, or limbic system structures. In psychiatric and neurologic conditions, mutism is often associated with other signs of catatonia. The authors review the literature on mutism, including psychiatric, neurologic, toxic-metabolic, and drug-induced causes. Methods to discriminate among the many causes of mutism in the clinical setting are discussed, and 22 new cases of mutism are reported to emphasize the wide differential diagnosis.

摘要

缄默症是精神疾病和神经疾病的常见表现。与缄默症相关的精神障碍包括精神分裂症、情感障碍、转换反应、分离状态和痴呆症。导致缄默症的神经疾病涉及基底神经节、额叶或边缘系统结构。在精神和神经疾病中,缄默症常与其他紧张症体征相关。作者回顾了关于缄默症的文献,包括精神、神经、毒性代谢和药物引起的病因。讨论了在临床环境中区分多种缄默症病因的方法,并报告了22例新的缄默症病例以强调广泛的鉴别诊断。

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Mutism: review, differential diagnosis, and report of 22 cases.缄默症:综述、鉴别诊断及22例报告
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引用本文的文献

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[Mutism in Han Kang's "Greek Lessons" - A reading from a psychiatric perspective].[韩江《希腊课》中的缄默症——从精神病学角度的解读]
Nervenarzt. 2025 Feb 26. doi: 10.1007/s00115-025-01817-7.
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A 44-Year-Old Man With Acute Mutism: Acute Stroke, Psychiatric Disorder, or Substance Abuse?一名44岁急性缄默症男性:急性中风、精神障碍还是药物滥用?
J Acute Med. 2022 Mar 1;12(1):34-38. doi: 10.6705/j.jacme.202203_12(1).0005.
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Catatonia in older adults: A systematic review.老年人的紧张症:一项系统综述。
World J Psychiatry. 2022 Feb 19;12(2):348-367. doi: 10.5498/wjp.v12.i2.348.
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Switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases.在两例紧张型精神分裂症病例中,换用阿立哌唑治疗残留性缄默症导致了不同的临床病程。
SAGE Open Med Case Rep. 2017 Feb 8;5:2050313X17692936. doi: 10.1177/2050313X17692936. eCollection 2017.
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Rapid Response of Long-Standing, Treatment-Resistant Non-Catatonic Mutism in Paranoid Schizophrenia with Single ECT session.单次电休克治疗对偏执型精神分裂症长期存在的、治疗抵抗性非紧张性缄默症的快速反应
N Am J Med Sci. 2014 Nov;6(11):591-4. doi: 10.4103/1947-2714.145480.
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Electroconvulsive Therapy for Long-term Mutism in a Case of Noncatatonic Paranoid Schizophrenia.电休克治疗对一例非紧张型偏执型精神分裂症所致长期缄默症的疗效
Innov Clin Neurosci. 2013 Jul;10(7-8):10-2.
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Mutism as the presenting symptom: three case reports and selective review of literature.以缄默症为首发症状:三例病例报告及文献综述
Indian J Psychol Med. 2010 Jan;32(1):61-4. doi: 10.4103/0253-7176.70542.
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