Targeting galectin-3 in myocardial infarction: a unique opportunity for biomarker-guided therapy.
作者信息
Frangogiannis Nikolaos G
机构信息
The Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Department of Microbiology and Immunology, Albert Einstein College of Medicine, 1300 Morris Park Avenue Forchheimer G46B, Bronx NY 10461, USA.
出版信息
Cardiovasc Res. 2023 Nov 25;119(15):2495-2496. doi: 10.1093/cvr/cvad156.
Abstract
摘要
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Cardiovasc Res. 2023 Nov 25;119(15):2536-2549. doi: 10.1093/cvr/cvad116.
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Cardiac fibrosis.心肌纤维化。
Cardiovasc Res. 2021 May 25;117(6):1450-1488. doi: 10.1093/cvr/cvaa324.
3
Genetic Deletion of Galectin-3 Alters the Temporal Evolution of Macrophage Infiltration and Healing Affecting the Cardiac Remodeling and Function after Myocardial Infarction in Mice.基因敲除半乳糖凝集素-3 改变了心肌梗死后小鼠巨噬细胞浸润和愈合的时间演变，影响了心脏重构和功能。
Am J Pathol. 2020 Sep;190(9):1789-1800. doi: 10.1016/j.ajpath.2020.05.010. Epub 2020 May 28.
4
Gal-3 (Galectin-3) and K3.1 Mediate Heterogeneous Cell Coupling and Myocardial Fibrogenesis Driven by βAR (β-Adrenoceptor) Activation.Gal-3（半乳糖凝集素-3）和 K3.1 介导βAR（β-肾上腺素能受体）激活驱动的异质细胞偶联和心肌纤维化。
Hypertension. 2020 Feb;75(2):393-404. doi: 10.1161/HYPERTENSIONAHA.119.13696. Epub 2019 Dec 16.
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Galectin-3 predicts left ventricular remodelling after anterior-wall myocardial infarction treated by primary percutaneous coronary intervention.半乳糖凝集素-3可预测经皮冠状动脉介入治疗的前壁心肌梗死后左心室重构。
Heart. 2017 Jan 1;103(1):71-77. doi: 10.1136/heartjnl-2016-309673. Epub 2016 Jul 27.
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