Hospital Privado de Rosario.
Grupo Gamma.
Rev Fac Cien Med Univ Nac Cordoba. 2023 Sep 29;80(3):289-300. doi: 10.31053/1853.0605.v80.n3.40408.
Desmoid-type fibromatosis (DF) is a rare monoclonal, fibroblastic proliferation characterized by an unpredictable and variable clinical course. We present the case of a 56-year-old woman who underwent total thyroidectomy for papillary thyroid carcinoma in 2012 and who developed a cervical mass at the left laterocervical level during follow-up, raising the diagnosis of tumor recurrence. Computed tomography of the neck showed solid formations with heterogeneous contrast uptake in the right lateral region of the neck. At the level of the thoracic operculum, a second 26-mm formation was observed that medially contacted the left lateral wall of the trachea. Lateral lymphadenectomy was performed, which was incomplete. Histology showed findings consistent with desmoid-type fibromatosis. DF are slowly proliferating, non-metastatic tumors with a highly invasive capacity that are usually present in familial adenomatous polyposis (FAP)-Gardner syndrome. Our case had a history of massive colonic polyposis and first-degree relatives of colorectal cancer.
韧带样型纤维瘤病（DF）是一种罕见的单克隆纤维母细胞增生，其临床过程不可预测且多变。我们报告了 1 例 56 岁女性患者，她于 2012 年因甲状腺乳头状癌行甲状腺全切除术，在随访中发现左侧颈侧区有颈肿块，诊断为肿瘤复发。颈部 CT 显示右侧颈外侧有实性肿块，伴有不均匀对比增强。在胸突水平，还观察到第二个 26mm 的肿块，内侧与气管左侧壁接触。行侧颈部淋巴结清扫术，但不完全。组织学检查显示符合韧带样型纤维瘤病的表现。DF 是一种生长缓慢、非转移性、具有高度侵袭性的肿瘤，通常见于家族性腺瘤性息肉病（FAP）-Gardner 综合征。我们的病例有大量结肠息肉病史和结直肠癌一级亲属。
