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成功使用 ALA-PDT 联合局部窄切缘切除术治疗大汗腺癌。

Successful treatment of hidradenocarcinoma using ALA-PDT combined with local narrow margin excision.

机构信息

Institute of Photomedicine Shanghai Skin Disease Hospital School of Medicine, Tongji University, Shanghai 200443, China; Skin Cancer Center, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200443, China; Anhui University of Science and Technology School of Medicine, Huainan 232001, China.

Department of Dermatology, Nanjing Medical University, Affiliated Wuxi Peoples Hospital, Wuxi 214023, China.

出版信息

Photodiagnosis Photodyn Ther. 2023 Dec;44:103791. doi: 10.1016/j.pdpdt.2023.103791. Epub 2023 Sep 28.

DOI:10.1016/j.pdpdt.2023.103791
PMID:37775040
Abstract

Hidradenocarcinoma is a rare malignancy of sweat gland differentiation. It is known for its high rate of recurrence and metastasis, which has a serious impact on human health and aesthetics. However, the treatment options for this disease are limited, making prompt and appropriate treatment is a daunting challenge. In this report, we present the first successful cure of hidradenocarcinoma using 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with local narrow margin excision on the left side of the forehead in an elderly woman. No recurrence during one year of follow-up after the combined therapy. This case will provide a valuable reference for more efficient management of similar cases in clinic.

摘要

汗腺癌是一种罕见的汗腺分化恶性肿瘤。它以高复发率和转移率为特征,严重影响人类健康和美观。然而,这种疾病的治疗选择有限,因此及时和适当的治疗是一个艰巨的挑战。在本报告中,我们首次成功地使用 5-氨基酮戊酸光动力疗法(ALA-PDT)联合局部窄切缘切除术治疗了一名老年女性左侧额部的汗腺癌。联合治疗后 1 年随访期间无复发。该病例为临床治疗类似病例提供了更有效的管理方法。

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