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血液灌流治疗地尔硫䓬与美托洛尔联合过量中毒

Charcoal hemoperfusion for the treatment of a combined diltiazem and metoprolol overdose.

作者信息

Anthony T, Jastremski M, Elliott W, Morris G, Prasad H

出版信息

Ann Emerg Med. 1986 Nov;15(11):1344-8. doi: 10.1016/s0196-0644(86)80622-9.

DOI:10.1016/s0196-0644(86)80622-9
PMID:3777591
Abstract

We describe the management of a 49-year-old woman who ingested 1,200 mg diltiazem and 500 mg metoprolol. The patient was bradycardic and hypertensive, requiring large doses of inotropic agents and temporary transvenous pacing. Charcoal hemoperfusion was used as an adjunct technique to hasten drug elimination; it rapidly lowered plasma drug levels, with a parallel improvement in the patient's clinical condition.

摘要

我们描述了一名49岁女性的治疗情况,她摄入了1200毫克地尔硫䓬和500毫克美托洛尔。患者出现心动过缓和高血压,需要大剂量的强心剂和临时经静脉起搏。活性炭血液灌流被用作辅助技术以加速药物清除;它迅速降低了血浆药物水平,同时患者的临床状况也得到了改善。

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Charcoal hemoperfusion for the treatment of a combined diltiazem and metoprolol overdose.血液灌流治疗地尔硫䓬与美托洛尔联合过量中毒
Ann Emerg Med. 1986 Nov;15(11):1344-8. doi: 10.1016/s0196-0644(86)80622-9.
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Life-threatening diphenhydramine overdose treated with charcoal hemoperfusion and hemodialysis.采用活性炭血液灌流和血液透析治疗危及生命的苯海拉明过量中毒。
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Diltiazem overdose: pharmacokinetics of diltiazem and its metabolites and effect of multiple dose charcoal therapy.地尔硫䓬过量:地尔硫䓬及其代谢产物的药代动力学以及多剂量活性炭疗法的效果
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[Accelerated elimination using hemoperfusion in a patient with phenobarbital intoxication].[使用血液灌流加速苯巴比妥中毒患者的清除]
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Diltiazem overdose: case report and review.地尔硫䓬过量:病例报告与综述
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Severe meprobamate poisoning: successful treatment with haemoperfusion.严重眠尔通中毒:血液灌流治疗成功案例
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Fatal diltiazem overdose: report of four cases and review of the literature.致命性地尔硫䓬过量:4例报告及文献复习
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Diltiazem. A reappraisal of its pharmacological properties and therapeutic use.地尔硫䓬。对其药理特性和治疗用途的重新评估。
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