血液灌流治疗地尔硫䓬与美托洛尔联合过量中毒

Charcoal hemoperfusion for the treatment of a combined diltiazem and metoprolol overdose.

作者信息

Anthony T, Jastremski M, Elliott W, Morris G, Prasad H

出版信息

Ann Emerg Med. 1986 Nov;15(11):1344-8. doi: 10.1016/s0196-0644(86)80622-9.

Abstract

We describe the management of a 49-year-old woman who ingested 1,200 mg diltiazem and 500 mg metoprolol. The patient was bradycardic and hypertensive, requiring large doses of inotropic agents and temporary transvenous pacing. Charcoal hemoperfusion was used as an adjunct technique to hasten drug elimination; it rapidly lowered plasma drug levels, with a parallel improvement in the patient's clinical condition.

摘要

我们描述了一名49岁女性的治疗情况，她摄入了1200毫克地尔硫䓬和500毫克美托洛尔。患者出现心动过缓和高血压，需要大剂量的强心剂和临时经静脉起搏。活性炭血液灌流被用作辅助技术以加速药物清除；它迅速降低了血浆药物水平，同时患者的临床状况也得到了改善。