东非地区宫颈癌女性患者的生存情况：系统评价和荟萃分析。
Survival of women with cervical cancer in East Africa: a systematic review and meta-analysis.
机构信息
Department of Midwifery, School of Nursing & Midwifery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
出版信息
J Obstet Gynaecol. 2023 Dec;43(2):2253308. doi: 10.1080/01443615.2023.2253308. Epub 2023 Sep 30.
BACKGROUND
The prognosis for cervical cancer varies greatly between nations. The disparity in cancer survival rates within nations is largely a result of disparities in public knowledge, the accessibility of cancer services, diagnosis and treatment. The purpose of this systematic review and meta-analysis is to assess the survival rate and associated factors among cervical cancer patients in East Africa.
METHODS
Literature search was carried out using Google scholar, PubMed/Medline, Embase and CINHAL. Covidence, a web-based program, was used to import studies for review process. PRISMA guidelines were followed. A total of 110 abstracts were identified from electronic sources. There were five duplicate articles removed. We looked at 105 papers' abstracts and titles, and we excluded 78 of them because they did not fit our inclusion criteria. We conducted a full-text analysis of the remaining 27 papers, leaving out 14 researches that did not fit our inclusion requirements. For final review, 13 studies were included. Using the Joanna Briggs Institute (JBI) assessment checklist, methodological quality was evaluated.
RESULTS
The included articles were cohort studies. They were conducted in Ethiopia, Uganda, Zimbabwe, Kenya, Sudan, Tanzania and Rwanda. One-year, two-year, three-year, four-year and five-year overall survival rates ranged from 67% to 92%, 55% to 84%, 44% to 53%, 32% to 47%, and 26% to 43%, respectively.
CONCLUSIONS
The pooled one-year, two-year, three-year, four-year and five-year survival rates of cervical cancer patients in East Africa were 84%, 71%, 50%, 39% and 36%, respectively. HIV status, late presentation, treatment modalities, older age and presence of comorbidities were the most commonly mentioned prognostic factors for survival.
PROSPERO REGISTRATION NUMBER
CRD42023402551.
背景
宫颈癌的预后在不同国家之间存在很大差异。造成国家内部癌症生存率差异的主要原因是公众知识、癌症服务的可及性、诊断和治疗方面的差异。本系统评价和荟萃分析的目的是评估东非宫颈癌患者的生存率和相关因素。
方法
使用 Google scholar、PubMed/Medline、Embase 和 CINHAL 进行文献检索。使用基于网络的程序 Covidence 将研究导入审查流程。遵循 PRISMA 指南。从电子资源中总共确定了 110 个摘要。删除了 5 个重复文章。我们查看了 105 篇论文的摘要和标题，并排除了 78 篇不符合我们纳入标准的论文。我们对其余 27 篇论文进行了全文分析，排除了 14 篇不符合我们纳入要求的研究。最终审查包括 13 项研究。使用 Joanna Briggs 研究所 (JBI) 评估检查表评估方法学质量。
结果
纳入的文章为队列研究。它们分别在埃塞俄比亚、乌干达、津巴布韦、肯尼亚、苏丹、坦桑尼亚和卢旺达进行。1 年、2 年、3 年、4 年和 5 年的总生存率范围为 67%至 92%、55%至 84%、44%至 53%、32%至 47%和 26%至 43%。
结论
东非宫颈癌患者的 1 年、2 年、3 年、4 年和 5 年总生存率分别为 84%、71%、50%、39%和 36%。HIV 状态、晚期就诊、治疗方式、年龄较大和合并症是生存的最常见预后因素。
PROSPERO 注册号：CRD42023402551。
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