Castelain M H, Donnadieu S, Vincent M, Fabre A, Laccourreye H
Ann Otolaryngol Chir Cervicofac. 1986;103(4):223-6.
Post-operative infections are studied about 150 patients distributed in five groups according to type of surgery (total pharyngolaryngectomy, hemilaryngectomy, bucco-pharyngectomy, cordectomy, cervicotomy). An antibiotic prophylaxis by penicillin G and metronidazole was prescribed for all groups excepted the last. Only sixteen patients (seven of whom in bucco-pharyngectomy group) developed a local infection, therefore these antibiotics are indicated until mucosa cicatrisation. Systematic bacteriologic study of cervical drains is useless because they are frequently positive with non-pathogenic germs and in case of local infection the responsible germ is different of the germ obtained by culture of drain.
对150例术后感染患者进行了研究，这些患者根据手术类型（全喉咽切除术、半喉切除术、颊咽切除术、声带切除术、颈部切开术）分为五组。除最后一组外，所有组均采用青霉素G和甲硝唑进行抗生素预防。只有16例患者（其中7例在颊咽切除术组）发生了局部感染，因此在黏膜愈合前均需使用这些抗生素。对颈部引流管进行系统的细菌学研究并无用处，因为引流管经常被非致病性细菌感染呈阳性，而且在发生局部感染时，致病细菌与通过引流管培养获得的细菌不同。
