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膝骨关节炎患者生活质量中神经性疼痛的流行情况及其干扰。

Prevalence and interference of neuropathic pain in the quality of life in patients with knee osteoarthritis.

机构信息

Grupo de Joelho, Instituto de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil; Hospital Sírio Libanês, São Paulo, SP, Brazil.

Grupo de Joelho, Instituto de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.

出版信息

Clinics (Sao Paulo). 2023 Sep 29;78:100287. doi: 10.1016/j.clinsp.2023.100287. eCollection 2023.

DOI:10.1016/j.clinsp.2023.100287
PMID:37778166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10757282/
Abstract

OBJECTIVE

With the aging of the population, more patients have complained of pain due to knee Osteoarthritis (OA), and the number of arthroplasties has also increased. The objective of this study is to evaluate the prevalence of the neuropathic pain component in candidates for Total Knee Replacement and the effects of this component on their quality of life.

METHODS

In this cross-sectional study, patients with OA candidates for knee arthroplasty in the present institution were evaluated using the pain detection questionnaire and the Visual Analog Pain (VAS) scale to measure the pain index and the presence of associated neuropathic pain. In addition, evaluation of the quality of life and functionality using the EQ5D and SF12 questionnaires and their relationship with cases of neuropathic pain were performed.

RESULTS

One hundred twenty-six patients were evaluated, and 71.4 % were female. The age ranged from 46 to 85 years, and about 70 % of the patients had some associated clinical comorbidity. Neuropathic pain was present in 28.6 % of the patients evaluated. Patients with neuropathic pain presented worse results in the VAS evaluation, in the care, pain, and anxiety domains of the EQ5D, and in the physical and mental scores of the SF12.

CONCLUSION

Neuropathic pain was present in 28.6 % of the patients with knee OA who are candidates for arthroplasty. Patients with associated neuropathic pain present a higher level of pain and worse quality of life scores. Recognizing this type of pathology is extremely important in fully monitoring gonarthrosis.

摘要

目的

随着人口老龄化,更多患有膝骨关节炎(OA)疼痛的患者抱怨疼痛,关节置换术的数量也有所增加。本研究旨在评估全膝关节置换候选者中神经性疼痛成分的患病率以及该成分对其生活质量的影响。

方法

在这项横断面研究中,对本机构的膝关节置换候选 OA 患者使用疼痛检测问卷和视觉模拟疼痛(VAS)量表进行评估,以测量疼痛指数和相关神经性疼痛的存在。此外,使用 EQ5D 和 SF12 问卷评估生活质量和功能,并评估其与神经性疼痛病例的关系。

结果

共评估了 126 名患者,其中 71.4%为女性。年龄范围为 46 至 85 岁,约 70%的患者有一些相关的临床合并症。评估的患者中有 28.6%存在神经性疼痛。患有神经性疼痛的患者在 VAS 评估、EQ5D 的护理、疼痛和焦虑领域以及 SF12 的身体和心理评分方面的结果更差。

结论

膝关节 OA 且需要接受关节置换的患者中有 28.6%存在神经性疼痛。伴有相关神经性疼痛的患者疼痛程度更高,生活质量评分更差。认识到这种类型的病理在全面监测膝关节骨关节炎方面非常重要。

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