• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

流式细胞术检测急性溶血性输血反应抗 Jk（b）IgM 的临床应用

Clinical Utility of Flow Cytometry for Detection of Anti-Jk IgM in Acute Haemolytic Transfusion Reaction.

机构信息

Department of Hematology, Mie University Hospital, Japan.

Department of Hematology, Yokkaichi Municipal Hospital, Japan.

出版信息

Intern Med. 2024 May 1;63(9):1273-1275. doi: 10.2169/internalmedicine.2639-23. Epub 2023 Sep 29.

DOI:10.2169/internalmedicine.2639-23
PMID:37779057
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11116007/
Abstract

Acute hemolytic transfusion reaction (AHTR) is a rare but life-threatening complication of transfusion. We herein report a case of anti-Jk IgM-related AHTR. Two hours after an 80-year-old man with myelodysplastic syndrome received a packed red blood cell (RBC) A/Rh/Jkc transfusion, he developed acute respiratory failure and a fever. Although he had tested negative in routine screening tests, the 37°C normal saline test was weakly positive for Jk. We confirmed the presence of anti-Jk IgM in the patient's serum by flow cytometry. This case demonstrates the potential utility of flow cytometry for IgM detection.

摘要

急性溶血性输血反应（AHTR）是输血的一种罕见但危及生命的并发症。本文报告了一例抗-Jk IgM 相关的 AHTR。一名 80 岁男性患有骨髓增生异常综合征，在接受了一袋 A/Rh/Jkc 型红细胞输注后 2 小时，他出现了急性呼吸衰竭和发热。尽管他在常规筛查试验中呈阴性，但 37°C 生理盐水试验对 Jk 呈弱阳性。我们通过流式细胞术确认了患者血清中存在抗-Jk IgM。该病例表明流式细胞术在 IgM 检测方面具有潜在的应用价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a808/11116007/02b7e409bc6c/1349-7235-63-1273-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a808/11116007/02b7e409bc6c/1349-7235-63-1273-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a808/11116007/02b7e409bc6c/1349-7235-63-1273-g001.jpg

相似文献

1
Clinical Utility of Flow Cytometry for Detection of Anti-Jk IgM in Acute Haemolytic Transfusion Reaction.流式细胞术检测急性溶血性输血反应抗 Jk（b）IgM 的临床应用
Intern Med. 2024 May 1;63(9):1273-1275. doi: 10.2169/internalmedicine.2639-23. Epub 2023 Sep 29.
2
Anti-M-Induced Delayed Hemolytic Transfusion Reaction.抗-M 引起的迟发性溶血性输血反应。
Lab Med. 2020 Jul 8;51(4):426-429. doi: 10.1093/labmed/lmz078.
3
Intraoperative Diagnosis and Management of Acute Hypotensive Blood Transfusion Reaction (AHTR): A Report of Two Cases.急性低血压输血反应（AHTR）的术中诊断与处理：两例报告
Am J Case Rep. 2018 Oct 29;19:1283-1287. doi: 10.12659/AJCR.910642.
4
A case of hyperhaemolysis syndrome in a pregnant Chinese woman with β-thalassemia during perinatal transfusion.围产期输血期间一名中国妊娠β-地中海贫血妇女发生高溶血性综合征
Transfus Med. 2021 Feb;31(1):24-29. doi: 10.1111/tme.12748. Epub 2020 Dec 16.
5
Acute Hemolytic Transfusion Reaction Due to the "Anti-E" Rhesus Antibody in a Patient with Crohn's Disease.克罗恩病患者因“抗-E”恒河猴抗体引发的急性溶血性输血反应
Clin Lab. 2019 Sep 1;65(9). doi: 10.7754/Clin.Lab.2019.190232.
6
Adverse transfusion reactions in patients with aplastic anaemia or myelodysplastic syndromes.再生障碍性贫血或骨髓增生异常综合征患者的输血不良反应
Vox Sang. 2019 May;114(4):349-354. doi: 10.1111/vox.12765. Epub 2019 Feb 28.
7
Red cell autoimmunization and alloimmunization in myelodysplastic syndromes: prevalence, characteristic and significance.骨髓增生异常综合征中的红细胞自身免疫和同种免疫：患病率、特征及意义。
Haematologica. 2019 Oct;104(10):e451-e454. doi: 10.3324/haematol.2018.215087. Epub 2019 Feb 28.
8
Severe acute haemolytic transfusion reaction secondary to a plasma incompatible group B platelet transfusion.因输注B型血浆不相容的血小板引发的严重急性溶血性输血反应。
Transfus Med. 2023 Apr;33(2):188-193. doi: 10.1111/tme.12938. Epub 2022 Nov 15.
9
Mechanisms responsible for delayed and immediate hemolytic transfusion reactions in a patient with anti-E + Jk(b)+ Di(b) and anti-HLA alloantibodies.一名具有抗 - E + Jk(b)+ Di(b) 和抗 HLA 同种抗体患者发生迟发性和速发性溶血性输血反应的相关机制
Immunopharmacol Immunotoxicol. 2004;26(4):645-52. doi: 10.1081/iph-200042369.
10
Delayed hemolytic transfusion reaction due to anti-Jk(a).抗Jk(a)导致的迟发性溶血性输血反应。
Acta Chir Iugosl. 2005;52(3):111-5. doi: 10.2298/aci0503111v.

本文引用的文献

1
Validation of a flow-cytometry-based red blood cell antigen phenotyping method.基于流式细胞术的红细胞抗原表型分析方法的验证
Vox Sang. 2023 Mar;118(3):207-216. doi: 10.1111/vox.13401. Epub 2023 Jan 12.
2
The Kidd (JK) Blood Group System.基德（JK）血型系统。
Transfus Med Rev. 2017 Jul;31(3):165-172. doi: 10.1016/j.tmrv.2016.10.003. Epub 2016 Nov 9.
3
An acute hemolytic transfusion reaction due to the "anti-c" rhesus antibody: A case report emphasizing the role of transfusion medicine.一例由“抗 - c”恒河猴抗体引起的急性溶血性输血反应：一份强调输血医学作用的病例报告
Asian J Transfus Sci. 2015 Jul-Dec;9(2):213-5. doi: 10.4103/0973-6247.154256.
4
A critical review of published methods for analysis of red cell antigen-antibody reactions by flow cytometry, and approaches for resolving problems with red cell agglutination.通过流式细胞术分析红细胞抗原-抗体反应的已发表方法的批判性评价，以及解决红细胞凝集问题的方法。
Transfus Med Rev. 2010 Jul;24(3):172-94. doi: 10.1016/j.tmrv.2010.03.001.
5
Immunogenicity of blood group antigens: a mathematical model corrected for antibody evanescence with exclusion of naturally occurring and pregnancy-related antibodies.血型抗原的免疫原性：一个针对抗体消失进行校正的数学模型，排除了天然存在的和与妊娠相关的抗体。
Blood. 2009 Nov 5;114(19):4279-82. doi: 10.1182/blood-2009-06-227793. Epub 2009 Aug 27.
6
An acute haemolytic transfusion reaction due to anti-Jk.由抗Jk抗体引起的急性溶血性输血反应。
Blood Transfus. 2007 Apr;5(2):102-6. doi: 10.2450/2007.0007-07.
7
Acute hemolytic transfusion reactions due to multiple alloantibodies including anti-E, anti-c and anti-Jkb.由多种同种抗体（包括抗 -E、抗 -c 和抗 -Jkb）引起的急性溶血性输血反应。
J Korean Med Sci. 2003 Dec;18(6):894-6. doi: 10.3346/jkms.2003.18.6.894.
8
A critique of the theoretical hazard of inter vs. intra-racial transfusion.关于种族间输血与种族内输血理论风险的评论
Transfusion. 1961 Jul-Aug;1:233-8. doi: 10.1111/j.1537-2995.1961.tb00048.x.
9
Application of flow cytometry to immunohematology.流式细胞术在免疫血液学中的应用。
J Immunol Methods. 1987 Jul 16;101(1):127-31. doi: 10.1016/0022-1759(87)90225-0.