Department of Neurology, National Hospital Organization, Sendai Medical Center, Japan.
Department of Neurology, Tohoku University Graduate School of Medicine, Japan.
Intern Med. 2024 May 1;63(9):1301-1303. doi: 10.2169/internalmedicine.2279-23. Epub 2023 Sep 29.
Streptococcus agalactiae is a rare cause of meningitis in healthy adults. We herein report a case of culture-negative Streptococcus agalactiae meningitis in a healthy adult which was diagnosed using the FilmArray Meningitis and Encephalitis Panel. A healthy 22-year-old man presented with a fever, headache, and neck stiffness. Despite negative results from blood and cerebrospinal fluid cultures, the diagnosis was confirmed using the FilmArray Meningitis and Encephalitis Panel. The patient was treated with dexamethasone, vancomycin, and ceftriaxone, and thereafter recovered completely. This report highlights the importance of being aware that Streptococcus agalactiae meningitis can occur in healthy individuals, and summarizes these features.
无乳链球菌是健康成年人中脑膜炎的罕见病因。本文报告了一例健康成年人中经 FilmArray 脑膜炎和脑炎检测 panel 确诊的无乳链球菌脑膜炎，该患者培养结果阴性。一名 22 岁健康男性因发热、头痛和颈项强直就诊。尽管血和脑脊液培养结果均为阴性，但经 FilmArray 脑膜炎和脑炎检测 panel 确诊。患者接受地塞米松、万古霉素和头孢曲松治疗后痊愈。本病例强调了认识到健康个体中也可能发生无乳链球菌脑膜炎的重要性，并总结了此类患者的特点。
