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健康年轻男女中B族链球菌定植的患病率及通过日常接触传播的可能性。

Prevalence of group B streptococcus colonization and potential for transmission by casual contact in healthy young men and women.

作者信息

Manning Shannon D, Neighbors Katie, Tallman Patricia A, Gillespie Brenda, Marrs Carl F, Borchardt Stephanie M, Baker Carol J, Pearlman Mark D, Foxman Betsy

机构信息

Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, USA.

出版信息

Clin Infect Dis. 2004 Aug 1;39(3):380-8. doi: 10.1086/422321. Epub 2004 Jul 16.

Abstract

Group B Streptococcus (GBS) causes disease in newborns, pregnant women, and adults with underlying medical conditions, but it is also a commensal organism that commonly colonizes the bowel. In this study, the prevalence of colonization was high among 241 women (34%) and 211 men (20%) living in a college dormitory; sexually experienced subjects had twice the colonization rates of sexually inexperienced participants. Other predictors of colonization varied by colonization site. Only 10 of the 142 roommate pairs had roommates who were both colonized with GBS, and 20% of these pairs shared identical strains, which is the same rate predicted by the population distribution. By contrast, a previous report found that 86% of co-colonized sex partners shared identical strains. GBS is likely transmitted by intimate contact, but transmission modes may vary by colonization site. Large prospective studies are needed to better understand colonization site-specific factors for GBS and to clarify potential transmission modes.

摘要

B族链球菌(GBS)可导致新生儿、孕妇以及有基础疾病的成年人患病,但它也是一种常见的共生生物,通常寄居于肠道。在本研究中,居住在大学宿舍的241名女性(34%)和211名男性(20%)中GBS定植率较高;有性经历的受试者定植率是无性经历参与者的两倍。其他定植预测因素因定植部位而异。142对室友中只有10对双方都被GBS定植,其中20%的配对菌株相同,这与根据人群分布预测的比例相同。相比之下,之前的一份报告发现,86%的共同定植的性伴侣菌株相同。GBS可能通过密切接触传播,但传播方式可能因定植部位而异。需要开展大型前瞻性研究,以更好地了解GBS定植部位特异性因素,并阐明潜在的传播方式。

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