Chakraborty Debarghya, Tabassum Humayra, Das Sowmitra
Internal Medicine, King's College University Hospital Trust, London, GBR.
Cureus. 2025 Mar 16;17(3):e80658. doi: 10.7759/cureus.80658. eCollection 2025 Mar.
Lemierre's syndrome is a rare complication of oropharyngeal infection characterized by septic thrombophlebitis in the internal jugular vein. Despite this being a common occurrence before the era of antibiotics, with beta-lactam antibiotic usage, this pathology has been a rare occurrence since the mid-1900s. Most cases are attributed to bacteraemia. However, in this case report, we present a middle-aged patient diagnosed with Lemierre's syndrome secondary to an atypical pharyngeal infection of A computed tomography (CT) scan of the neck visualized the internal jugular vein thrombus, aiding in the diagnosis of the condition. He further develops pulmonary complications from the dissemination of thrombus from the internal jugular vein. This case emphasizes the need for higher clinical suspicion to ensure timely management of the condition. Similarly, it demonstrated how a multidisciplinary approach and appropriate follow-up are crucial in the successful management of these patients. It also highlights the requirement for larger population-based studies to ensure definitive and evidence-based clinical guidelines to reduce the morbidity and mortality from this rare yet serious condition of Lemierre's syndrome.
勒米尔综合征是口咽感染的一种罕见并发症，其特征为颈内静脉脓毒性血栓性静脉炎。尽管在抗生素时代之前这种情况很常见，但自20世纪中叶以来，随着β-内酰胺类抗生素的使用，这种病症已很少见。大多数病例归因于菌血症。然而，在本病例报告中，我们介绍了一名中年患者，该患者被诊断为继发于非典型咽部感染的勒米尔综合征。颈部计算机断层扫描（CT）显示了颈内静脉血栓，有助于诊断该病症。他因颈内静脉血栓扩散进一步出现肺部并发症。该病例强调需要提高临床怀疑度以确保及时治疗该病症。同样，它展示了多学科方法和适当的随访在成功治疗这些患者中的关键作用。它还强调需要开展基于更大人群的研究，以确保制定明确且基于证据的临床指南，从而降低这种罕见但严重的勒米尔综合征的发病率和死亡率。
