用于识别钯（II）的基于简单香豆素的荧光探针及其活细胞成像
Simple Coumarin-Based Fluorescent Probe for Recognition of Pd(II) and Its Live Cell Imaging.
作者信息
Zhang Xiangyang, Xu Yaodan, Shen Youming, Wang Feifei
机构信息
College of Chemistry and Material Engineering, Hunan University of Arts and Science, Changde 415000, P. R. China.
Changde Engineering Technology Research Center of Biomedical Polymer Materials, Changde 415000, P. R. China.
出版信息
ACS Omega. 2023 Sep 12;8(38):35121-35126. doi: 10.1021/acsomega.3c04626. eCollection 2023 Sep 26.
A simple coumarin hydrazine Schiff base bearing a thioether recognition fragment (compound ) has been rationally designed and easily prepared. exhibited an excellent selectivity for Pd(II) and a low detection limit of 65 nM (S/N = 3). The fluorescence emission intensities of at 495 nm were linear to Pd(II) concentrations in a wide range from 0 to 80 μM. Moreover, has been well used in fluorescence imaging of Pd(II) in living A549 cells. as a simple coordination-based fluorescent probe will inspire the researchers to develop a polymer for selective detection and adsorption of Pd(II).
一种带有硫醚识别片段的简单香豆素肼席夫碱（化合物 ）已被合理设计并易于制备。该化合物对 Pd(II) 表现出优异的选择性，检测限低至 65 nM（信噪比 = 3）。在 495 nm 处该化合物的荧光发射强度与 Pd(II) 浓度在 0 至 80 μM 的宽范围内呈线性关系。此外，该化合物已成功用于活的 A549 细胞中 Pd(II) 的荧光成像。作为一种简单的基于配位的荧光探针，该化合物将激励研究人员开发一种用于选择性检测和吸附 Pd(II) 的聚合物。
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