Sheth Chandni, Huber Rebekah S, Renshaw Perry F, Yurgelun-Todd Deborah A, McGlade Erin C
School of Medicine, Department of Psychiatry, University of Utah, Salt Lake City, UT, USA.
Diagnostic Neuroimaging Laboratory, University of Utah, Salt Lake City, UT, USA.
J Early Adolesc. 2023 Jun;43(6):720-745. doi: 10.1177/02724316221117508. Epub 2022 Nov 14.
There has been concern about the potential sequelae of mild traumatic brain injury (mTBI) in children. This study used data from the Adolescent Brain Cognitive Development (ABCD) study to investigate associations between mTBI and behavior and sleep in school-aged children. Generalized additive mixed models were run to examine the association between TBI and parent-reported Child Behavior Checklist and Sleep Disturbance Scale for Children scores. mTBI with or without loss of consciousness (LOC) in 9- and 10-year old children was associated with 1) higher internalizing, externalizing and total problems and 2) greater sleep disturbance scores on the CBCL. The study also demonstrated a higher incidence of mTBI with and without LOC in boys compared to girls. This study shows a statistically significant but modest association between mTBI and behavioral and sleep changes, suggesting that in a non-clinical, sociodemographically diverse community sample of school-aged children mTBI does not result in clinically significant behavioral or psychological sequelae.
儿童轻度创伤性脑损伤(mTBI)的潜在后遗症一直受到关注。本研究使用青少年大脑认知发展(ABCD)研究的数据,调查mTBI与学龄儿童行为和睡眠之间的关联。采用广义相加混合模型来检验创伤性脑损伤(TBI)与家长报告的儿童行为检查表(Child Behavior Checklist)及儿童睡眠障碍量表(Sleep Disturbance Scale for Children)得分之间的关联。9岁和10岁儿童有无意识丧失(LOC)的mTBI与以下情况相关:1)内化、外化及总问题得分更高;2)儿童行为检查表(CBCL)上的睡眠障碍得分更高。该研究还表明,与女孩相比,男孩发生有无LOC的mTBI的发生率更高。本研究显示,mTBI与行为及睡眠变化之间存在统计学上显著但程度较轻的关联,这表明在一个非临床、社会人口统计学特征多样的学龄儿童社区样本中,mTBI不会导致具有临床意义的行为或心理后遗症。