Chen Yiyang, Liu Juanjuan, Zhang Jialing, Yang Liping, Jin Ling
Gansu University of Traditional Chinese Medicine, Lanzhou, Gansu Province, China.
Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-constructed By Gansu Province & MOE of PR China, Lanzhou, Gansu Province, China.
Heliyon. 2023 Sep 25;9(10):e20325. doi: 10.1016/j.heliyon.2023.e20325. eCollection 2023 Oct.
Salvia miltiorrhiza (Salvia miltiorrhiza Radix et Rhizoma) is the dried root and rhizome of Bge., a plant of the labiate family. It is a type of traditional Chinese medicine that can promote blood circulation for removing blood stasis. It is often used to treat cardiovascular and cerebrovascular diseases in a clinic.: High-quality Chinese herbal medicines are the premise of the safe and effective use of Traditional Chinese Medicine (TCM) in clinics. We aim to prove the rationality of the traditional identification method, namely, 'the redder the root colour and the thicker the root, the better is the quality', to use the morphological features of Salvia miltiorrhiza as the main index to quickly and directly evaluate its quality.
By referring to relevant ancient books, domestic and foreign literature, and academic papers, we summarised the research progress regarding the morphological features, functional substances, pharmacological action, and clinical efficacy of Salvia miltiorrhiza.
The redder the colour, the thicker the root, and the denser the texture, the better is the quality of Salvia miltiorrhiza. In Salvia miltiorrhiza, tanshinone Ⅱ and salvianolic acid B are the main functional substances that protect the cardiovascular and cerebrovascular functions. The higher the content of these two functional substances, the better is the clinical efficacy of Salvia miltiorrhiza.
The research idea of the correlation between the 'morphological features, functional substances, pharmacological action, and clinical efficacy' can be applied to evaluate the quality of Salvia miltiorrhiza. This research idea and method can also be applied to more Chinese herbal medicines.
丹参是唇形科植物丹参干燥的根及根茎。它是一种能活血化瘀的传统中药，临床上常用于治疗心脑血管疾病。优质中药材是中药临床安全有效应用的前提。我们旨在证明传统鉴别方法“根色越红、根越粗壮，质量越好”的合理性，以丹参的形态特征作为主要指标来快速直接地评价其质量。
通过查阅相关古籍、国内外文献及学术论文，总结了丹参在形态特征、功能物质、药理作用及临床疗效方面的研究进展。
丹参颜色越红、根越粗壮、质地越致密，质量越好。在丹参中，丹参酮Ⅱ和丹酚酸B是保护心脑血管功能的主要功能物质。这两种功能物质的含量越高，丹参的临床疗效越好。
“形态特征、功能物质、药理作用及临床疗效”之间相关性的研究思路可用于评价丹参的质量。该研究思路和方法也可应用于更多的中药材。
