Berkwits L, Yarkony G M, Lewis V
Arch Phys Med Rehabil. 1986 Nov;67(11):831-3.
Fifteen years after spinal cord injury and 14 years after development of a sacral pressure ulcer in a paraplegic man, a squamous cell carcinoma was found on biopsy during surgical reconstruction of the pressure ulcer. The patient refused the extensive surgery necessary to remove the infiltrating tumor, and the wound was closed with a latissimus dorsi flap. Pressure ulcers remain a problem in spinal cord injured and other disabled patients. Malignant degeneration (Marjolin's ulcer) in chronic pressure ulcers and other chronic skin ulcerations may become more widespread as the life span of spinal cord injured patients increases.
一名截瘫男性脊髓损伤15年后出现骶部压疮，14年后在对该压疮进行手术重建时活检发现鳞状细胞癌。患者拒绝了切除浸润性肿瘤所需的广泛手术，伤口用背阔肌皮瓣封闭。压疮仍是脊髓损伤患者及其他残疾患者面临的一个问题。随着脊髓损伤患者寿命的延长，慢性压疮及其他慢性皮肤溃疡中的恶性变（Marjolin溃疡）可能会更加普遍。
