Klingberg M, Klingberg H, Klingberg F
Biomed Biochim Acta. 1986;45(8):1021-8.
Hooded rats of the Long-Evans strain with bilateral symmetric lesions of the nucleus reticularis pontis oralis (RPO) displayed locomotor hyperactivity in the open field (OF) compared with their preoperative values. Their locomotor velocity and their climbing rate were significantly enhanced. Habituation in the OF was significantly weakened. The lesioned rats were unable to acquire any active avoidance responses in a Y-maze or a jump test. They were unable to correctly perform preoperatively learned avoidance responses and could not relearn the tasks. Reaction times to the conditioned stimulus increased and more often the rats escaped only after the onset of the punishment; even their escape responses were instable. The lesioned rats were neurologically inconspicuous. One can assume that the RPO participates in a functional system for control and recall of learned (not inborn) programs.
与术前值相比，患有双侧桥脑嘴侧网状核（RPO）对称损伤的长-伊文斯品系有帽大鼠在旷场（OF）中表现出运动活动亢进。它们的运动速度和攀爬速率显著提高。在旷场中的习惯化显著减弱。损伤大鼠在Y迷宫或跳跃试验中无法获得任何主动回避反应。它们无法正确执行术前学会的回避反应，也无法重新学习这些任务。对条件刺激的反应时间增加，而且大鼠更常在惩罚开始后才逃脱；甚至它们的逃脱反应也不稳定。损伤大鼠在神经学上无明显异常。可以推测，RPO参与了一个用于控制和回忆习得（非先天）程序的功能系统。
