Azarbakhsh Habibollah, Dehghani Seyed S, Hassanzadeh Jafar, Janfada Maryam, Razeghi Ahmadreza, Mirahmadizadeh Alireza
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Lung India. 2023 Sep-Oct;40(5):412-417. doi: 10.4103/lungindia.lungindia_530_22.
Asthma is a globally important non-communicable disease with major public health consequences. The aim of this study was to determine the mortality rate and years of life lost (YLL) due to asthma in southern Iran.
All deaths due to asthma in Fars province from the electronic population-based death registration system (EDRS) were obtained. Crude mortality rate, age-standardized mortality rate, YLL and YLL rate data were calculated. The JoinPoint Regression method was used to examine the trend.
During the 16-year study period (2004-2019), 1167 deaths due to asthma occurred in Fars province among which 54.7% (638 cases) were men and 29.6% (346 cases) were in the age group of 70-79 years. Crude mortality rate of asthma had decreased by 121% and 84% in males and females, respectively from 2004 to 2019. The total years of life lost due to asthma during the 16-year study period were 7697 (0.24 per 1000 people) in men, 6882 (0.22 per 1000 people) in women. According to the join point regression analysis, the 16-year trend of YLL rate due to premature mortality was decreasing: the annual percent change (APC) was -5.6% (95% CI -8.2 to -2.9, P = 0.001) for males, -4.4% (95% CI -7.3 to -1.4, P = 0.008) for females.
The trend of mortality and years of life lost due to asthma has decreased significantly during the years of study, although in some age groups, especially the age group of 45-59 years which has the highest number of years of life lost, this trend has been constant and unchanged. It is necessary to conduct other studies to investigate the possible reasons for this unchanged trend in vulnerable age groups.
哮喘是一种在全球范围内具有重要公共卫生影响的非传染性疾病。本研究旨在确定伊朗南部因哮喘导致的死亡率和寿命损失年数（YLL）。
从基于人群的电子死亡登记系统（EDRS）中获取法尔斯省所有因哮喘导致的死亡病例。计算粗死亡率、年龄标准化死亡率、YLL和YLL率数据。采用JoinPoint回归方法分析趋势。
在16年的研究期（2004 - 2019年）内，法尔斯省有1167例因哮喘死亡，其中男性占54.7%（638例），70 - 79岁年龄组占29.6%（346例）。从2004年到2019年，男性和女性哮喘粗死亡率分别下降了121%和84%。在16年研究期内，男性因哮喘导致的总寿命损失年数为7697年（每1000人0.24年），女性为6882年（每1000人0.22年）。根据JoinPoint回归分析，过早死亡导致的YLL率的16年趋势呈下降趋势：男性的年变化百分比（APC）为-5.6%（95%CI -8.2至-2.9，P = 0.001），女性为-4.4%（95%CI -7.3至-1.4，P = 0.008）。
在研究期间，哮喘导致的死亡率和寿命损失年数趋势显著下降，尽管在某些年龄组，特别是寿命损失年数最多的45 - 59岁年龄组，这一趋势保持不变。有必要开展其他研究来调查这一易受影响年龄组中这一不变趋势的可能原因。
